Genomic analysis of the first laboratory-mouse papillomavirus. [PDF]
A papillomavirus (PV) that naturally infects laboratory mice will provide an extremely valuable tool for PV research. We describe here the isolation, cloning and molecular analysis of the first novel laboratory-mouse PV, designated MusPV. This agent,
Joh, J +6 more
core
Breast cancer is the most common malignancy in the female sex; although recent therapies have significantly changed the natural history of this cancer, it remains a significant challenge.
Chiara Rossi +7 more
doaj +1 more source
Enhanced Broad-Spectrum Efficacy of an L2-Based mRNA Vaccine Targeting HPV Types 6, 11, 16, 18, with Cross-Protection Against Multiple Additional High-Risk Types [PDF]
Background: Current L1-based human papillomavirus (HPV) vaccines provide type-specific protection but offer limited cross-protection against non-vaccine HPV types. Therefore, developing a broad-spectrum HPV vaccine is highly desirable.
Nobuhisa Mizuki +10 more
core +1 more source
We used our mouse papillomavirus (MmuPV1) model to test the hypothesis that two primary psychoactive ingredients of marijuana, Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), promote papillomavirus persistence in the oral mucosa of infected mice. We
Sarah A. Brendle +9 more
doaj +1 more source
Tumorigenicity of primary mouse fibroblasts transformed by bovine papillomavirus type 1.
Cell lines transformed by bovine papillomavirus type 1 DNA were established from transfected primary fibroblast cultures of C57BL/6 mice. Southern blot analysis revealed that most of the viral DNA in the cells was in episomal oligomeric form. These cell lines were tested for tumorigenicity in nude mice in comparison to properties associated with ...
R, Mäntyjärvi +5 more
openaire +1 more source
Papillomas and carcinomas associated with a papillomavirus in European harvest mice (Micromys minutus). Vet Pathol 25 [PDF]
. Papillomaviruses, group-specific papillomavirus antigens, or extrachromosomal papillomavirus DNA were detected in cutaneous, mucocutaneous, and pulmonary tumors affecting a colony of European harvest mice (Micromys minutus).
C. Knupp +9 more
core
Background Carcinosarcomas of the gynecologic tract, previously referred to as malignant mixed müllerian/mesodermal tumor, are devastating malignancies that remain poorly studied due to their rarity and the lack of relevant model systems.
Jason Murray +4 more
doaj +1 more source
Strategies for studying mouse and human immune responses to human papillomavirus type 16.
Cytotoxic T lymphocytes (CTL) are an important protective mechanism in viral infection and can be effective against tumours. We have investigated the tumour-associated E6 and E7 genes of human papillomavirus type 16 as CTL targets. In H-2b mice we have defined epitopes in E6 and E7 which can readily generate CTL in vivo and we have shown that HLA-A2.1 ...
Beverley, P +9 more
openaire +2 more sources
Gender Difference in DNA Damage Induced by the Environmental Carcinogen Dibenzo[<i>def,p</i>]chrysene Individually and in Combination with Mouse Papillomavirus Infection in the Mouse Oral Cavity. [PDF]
Chen KM +9 more
europepmc +1 more source
Mammal-infecting DNA viruses identified in lemurs and rodents in Madagascar mirror the evolutionary history of their hosts. [PDF]
Paietta EN +13 more
europepmc +1 more source

