Results 111 to 120 of about 38,676 (197)
Studies of human papillomaviruses (HPVs) are hampered by the lack of a conventional culture system because HPV completes its life cycle only in fully differentiated human tissue. To overcome this obstacle, the athymic mouse xenograft system has been used to study the pathogenesis of HPV 11 and to develop neutralizing assays for vaccine development ...
Brown, Darron R. +5 more
openaire +2 more sources
What's new? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies +12 more
wiley +1 more source
In vivo assessment of imoxide and diluted vitamin C’s inhibitory effects on cervical cancer in mice [PDF]
Objective(s): Cervical cancer, the fourth most common malignancy among women, is strongly associated with high-risk human papillomavirus (HPV) infection.
Toktam Dehghani +10 more
doaj +1 more source
History of Cervical Cancer and the Role of the Human Papillomavirus, 1960-2000
Annotated and edited transcript of a Witness Seminar held on 13 May 2008. Introduction by Professor Anne M Johnson, Division of Population Health and Institute for Global Health, UCL.
Reynolds, LA, Tansey, EM
core
Characterization of viral nanoparticles derived from mouse papillomavirus [PDF]
The L1 and L2 capsid proteins of papillomaviruses are characterized by the ability to self- assemble into viral capsids, which can be divided into pseudovirions (PsVs) and virus-like particles (VLPs) by inner content.
Vomáčka, Petr
core
Abstract BACKGROUND Rabies continues to pose a major public health threat, causing approximately 59 000 deaths each year, especially in regions with limited resources where high costs restrict vaccine access. Safer and scalable vaccine platforms, such as virus‐like particles, are promising alternatives, but their production is highly sensitive to ...
Júlia Públio Rabello +8 more
wiley +1 more source
To study the immune response to human papillomavirus type 16, a mouse model was developed using a mouse keratinocyte cell line expressing the E7 protein. This line was grafted onto syngeneic mice to form a differentiated epithelium, thus closely mimicking the natural infection.
C S, McLean +4 more
openaire +2 more sources
The role of human papillomavirus (HPV) E6 proteins as a risk factor for oesophageal cancer
Includes bibliographical references (leaves 74-83).Oesophageal squamous cell carcinoma (OSCC) is a major cancer in South Africa, affecting mainly black males.
Ross-Innes, Caryn Sarah
core
Papillomavirus Infection Requires γ Secretase
The mechanism by which papillomaviruses breach cellular membranes to deliver their genomic cargo to the nucleus is poorly understood. Here, we show that infection by a broad range of papillomavirus types requires the intramembrane protease γ secretase ...
Christopher Buck +5 more
core +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source

