Results 111 to 120 of about 887,744 (175)

Sclareol Inhibit Cell Growth and Induces Apoptosis via Activation of p53/p21 Signaling Pathways in Human Oral Squamous Cell Carcinoma Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The Schematic representation of the possible molecular mechanism of sclareol induces apoptosis through p53 and p21‐associated signaling in KB cells. ABSTRACT One of the most common prevalent forms of cancer in the world is oral squamous cell carcinoma (OSCC).
Anandhi Nallu, Suresh Kathiresan, Theerthu Azhamuthu, Hemavardhani Ramadoss, Nihal Ahamed Abulkalam Asath, Pugazhendhi Ravichandran, Rajeswari Vasu   +6 more
wiley   +1 more source

A study of genital human papillomavirus (HPV) infection and antibody response in heterosexually active South African couples [PDF]

, 2011
This study constitutes the first report on type-specific human papillomavirus (HPV) concordance and transmission in heterosexually active couples that are human immunodeficiency (HIV)-seronegative, HIV-seropositive or HIV-discordant and in which 71% of ...
Mbulawa, Zizipho Ziphozakhe Anita
core   +1 more source

Mouse papillomavirus type 1 (MmuPV1) DNA is frequently integrated in benign tumors by microhomology-mediated end-joining. [PDF]

PLoS Pathog, 2021
Yu L, Majerciak V, Xue XY, Uberoi A, Uberoi A, Lobanov A, Chen X, Cam M, Hughes SH, Lambert PF, Zheng ZM.   +10 more
europepmc   +1 more source

Cyclins and Cyclin‐Dependent Kinases: Structure, Biological Functions, and Innovative Targeting Strategies in Cancer

MedComm, Volume 7, Issue 9, September 2026.
This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng, Zhipeng Shen, Yuanfang Wu, Xingze Huang, Zhongyuan Zhang, Jiangyu Liu, Qichun Wei, Wenhao Chen, Ye Chen, Liang Xu   +9 more
wiley   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

MedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait, Anna Cargnoni, Franco Scaldaferri, Loris Lopetuso, Antonietta Rosa Silini, Ornella Parolini   +5 more
wiley   +1 more source

Antitumor Activity of Combined Topoisomerase Inhibition and FLASH Radiotherapy in Head and Neck Carcinoma Biomodels

MedComm, Volume 7, Issue 9, September 2026.
We report a proof‐of‐concept combination of topoisomerase inhibition and FLASH radiotherapy showing enhanced antitumor activity in head and neck carcinoma biomodels, supporting further investigation of this strategy in more clinically representative models and treatment settings. ABSTRACT Locally advanced head and neck carcinoma remains associated with
Patrizia Sarogni, Nicoletta Brindani, Valentina Frusca, Melissa Santi, Andrea Cavalieri, Mariagrazia Celentano, Michele Menicagli, Andrea Marranci, Andrea Ghelli Luserna di Rorà, Federico Purificato, Michela Nigro, Noemi Giannini, Alessandra Gonnelli, Giovanni Gadducci, Fabio Di Martino, Fabiola Paiar, Marco De Vivo, Valerio Voliani   +17 more
wiley   +1 more source

Identification and Characterization of MmuPV1 Causing Papillomatosis Outbreak in an Animal Research Facility

Viruses
Mouse papillomavirus (MmuPV1) is the first papillomavirus known to infect laboratory mice, making it an irreplaceable tool for research on papillomaviruses. Despite wide use, standardized techniques for conducting MmuPV1 animal research are lacking.
Vladimir Majerciak, Kristin E. Killoran, Lulu Yu, Deanna Gotte, Elijah Edmondson, Matthew W. Breed, Renee E. King, Melody E. Roelke-Parker, Paul F. Lambert, Joshua A. Kramer, Zhi-Ming Zheng   +10 more
doaj   +1 more source

Supraphysiological 25‐Hydroxyvitamin D3 and Calcipotriol Induce Reactive Oxygen Species, Mitochondrial Dysfunction and Apoptosis in HeLa Cervical Cancer Cells

FASEB BioAdvances, Volume 8, Issue 9, September 2026.
Supraphysiological 25(OH)D3 and calcipotriol induced ROS accumulation or redox disturbance, increased mitochondrial membrane depolarization, reduced antioxidant enzyme activity, and caused apoptotic cell death in HeLa cells. ABSTRACT Cervical cancer remains a major global health challenge, necessitating continued advances in therapeutic strategies ...
Hoi Ching Cherry Chan, Sachin Bhoora, Esther Zhou, Sumari Marais, Tahir S. Pillay, Rivak Punchoo   +5 more
wiley   +1 more source

hTERT Immortalization Stabilizes Human Umbilical Cord MSCs and Maintains Their Small Extracellular Vesicles With Preserved Immunomodulatory Activity and Primordial Follicle‐Activating Capacity

Aging Cell, Volume 25, Issue 9, September 2026.
hTERT immortalization stabilizes hUCMSC‐derived sEV function by alleviating cellular senescence and preserving young‐like cargo profiles. H11‐sEVs retain immunomodulatory activity, primordial follicle‐activating capacity, and ovarian protective effects.
Yating Chen, Wei Liu, Ying Tian, Xinyu Wang, Haonan Fan, Mingyu Yang, Feiyang Diao, Jing Li   +7 more
wiley   +1 more source

The Role of Oncogenic Viruses in the Pathogenesis of Sporadic Breast Cancer: A Comprehensive Review of the Current Literature

Pathogens
Breast cancer is the most common malignancy in the female sex; although recent therapies have significantly changed the natural history of this cancer, it remains a significant challenge.
Chiara Rossi, Frediano Socrate Inzani, Stefania Cesari, Gianpiero Rizzo, Marco Paulli, Paolo Pedrazzoli, Angioletta Lasagna, Marco Lucioni   +7 more
doaj   +1 more source