Hippo pathway disruption and YAP1 activation in anogenital papillary squamous intraepithelial lesion
Disruption of the Hippo Pathway with YAP1 activation is a consistent finding in papillary squamous intraepithelial lesions and may underlie their altered epithelial maturation and HPV E6/E7 expression patterns, providing new insight into the pathogenesis of this distinct low‐risk HPV‐associated lesion.
Gloria Zhang +4 more
wiley +1 more source
Nucleotide Sequence and Characterization of Human Papillomavirus Type 83, a Novel Genital Papillomavirus [PDF]
Studies of human papillomaviruses (HPV) are hampered by the lack of a conventional culture system, because HPV completes its life cycle only in fully differentiated human tissue. To overcome this obstacle, the athymic mouse xenograft system has been used
Fife, Kenneth H. +3 more
core +1 more source
Mitochondria‐Targeting Moieties Based on N‐Tethered Pyridinium Cations
Pyridinium cations were benchmarked as mitochondria‐targeting moieties in a panel of N‐tethered fluorescent‐, bioactive‐, and inert‐cargo conjugates. 3,5‐Diphenylpyridinium (DPPy+) is a competent triphenylphosphonium (TPP+) surrogate, combining high mitochondria‐targeting efficiency with lower intrinsic effects on mitochondrial function.
Ivan Džajić +27 more
wiley +2 more sources
Viruses, Periodontitis, and Systemic Diseases
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte +2 more
wiley +1 more source
Cell cycle control and its modulation in HPV infected cells [PDF]
A key effect of human papillomavirus (HPV) infection is to disrupt the normal cell cycle in order to subvert the cellular DNA replication machinery. Morphologically, condylomata induced by high and low risk HPV types cannot be distinguished and many ...
Lyman, Rachel C.
core
In Vitro Transformation by Bovine Papillomavirus [PDF]
We have studied tumorigenic transformation of mouse tissue culture cells by bovine papillomavirus (BPV) as a model of papillomavirus-induced cell proliferation.
Lowy, Douglas R. +3 more
core +1 more source
High risk human papillomavirus and Epstein Barr virus in human breast milk
Background Multiple viruses, including human immunodeficiency virus, Epstein Barr virus (EBV) and mouse mammary tumour virus have been identified in human milk. High risk human papillomavirus (HPV) sequences have been identified in breast cancer. The aim
Glenn Wendy K +2 more
doaj +1 more source
The effect of photodynamic therapy in head and neck cancer: A comprehensive review of in vivo models
This review evaluates Photodynamic Therapy (PDT) in in vivo head and neck cancer models. PDT effectively generates ROS, reducing tumor growth, cell proliferation and angiogenesis while enhancing survival and immune responses. However, methodological heterogeneity highlights the urgent need for standardized dosimetric protocols to ensure reproducibility
Bibiana Padilha de Menezes da Silva +5 more
wiley +1 more source
Chimeric Papillomavirus-like Particles [PDF]
We have constructed chimeric papillomavirus-like particles (CVLPs) by replacing the 34-carboxy-terminal amino acids of the HPV 16 L1 protein with various parts of the HPV 16 E7 protein.
Zhou, Jian +7 more
core +1 more source
Hypoxia Induces a Mitotic Survival Advantage After Radiotherapy in Head and Neck Cancer Cells
Hypoxic tumor environments significantly limit radiotherapy effectiveness against cancer, particularly in head and neck squamous cell carcinoma (HNSCC). Here, the authors tracked hypoxic and post‐hypoxic cells using a hypoxia‐fate mapping system in human papillomavirus (HPV)‐positive and HPV‐negative HNSCC models.
Marilyn Wegge +3 more
wiley +1 more source

