Results 61 to 70 of about 29,777 (280)

Live-cell visualization of intracellular interaction between a nuclear migration protein (hNUDC) and the thrombopoietin receptor (Mpl). [PDF]

PLoS ONE, 2012
We previously demonstrated that endogenous hNUDC and Mpl co-localized in the perinuclear and cytoplasmic regions of megakaryocyte cells by indirect immunofluorescence.
Yuan-Bin Zheng, Ying-Ying Xiao, Peng Tan, Qing Zhang, Peilin Xu   +4 more
doaj   +1 more source

Understanding Operando Water Management in Hydroxide‐Exchange‐Membrane Fuel Cells

Advanced Materials Interfaces, EarlyView.
Effective water management is vital for high‐performance hydroxide‐exchange‐membrane fuel cells. Using a custom water‐flux station, this study quantifies how membrane thickness, microporous layers, and operating conditions dictate internal water transport.
Catherine M. Weiss, Shiyi Wang, Brian P. Setzler, Yushan Yan, Adam Z. Weber   +4 more
wiley   +1 more source

Interface Engineering of Porous Transport Layer‐Catalyst Layer in Proton Exchange Membrane Water Electrolyzers: A Comprehensive Review

Advanced Materials Interfaces, EarlyView.
The PTL–CL interface plays a decisive role in PEMWE performance by governing electron conduction, water supply, oxygen removal, catalyst utilization, and interfacial stability. This review summarizes interface‐related resistance sources, characterization methods, and engineering strategies, highlighting rational PTL–CL interface design for low‐cost ...
Aobo Wan, Zhengkai Tu
wiley   +1 more source

Penalized Likelihood-Based Estimation of Stratified Semiparametric Cox Models Under Partly Interval Censoring. [PDF]

Biom J
ABSTRACT In survival data analysis, the stratified Cox model becomes a popular option when the proportional hazards assumption of the conventional Cox model does not hold for certain covariates. For a stratified Cox model, when the observed survival times contain only right censoring, the method of maximum partial likelihood can still be implemented ...
Ma J, Webb A, Manuguerra M, Hudson HM.
europepmc   +2 more sources

TPO/Mpl Studies in Agnogenic Myeloid Metaplasia

, 2005
Background Agnogenic myeloid metaplasia (AMM) is one of the Philadelphia chromosome negative myeloproliferative disorder and is diagnosed by hyperplasia of atypical megakaryocytes, hepatosplenomegaly, extramedullary hematopoiesis and bone marrow fibrosis.
Hemavathy Kirugaval C, Novetsky Allan D, Hashmi Gazala, Suppiah Kathir, Wang Jen C   +4 more
core   +1 more source

Revealing the Nanoscale Morphology Changes of Polymer Electrolyte Membrane Fuel Cell Catalyst Layers due to Conditioning

Advanced Science, EarlyView.
We apply ex situ and in situ scanning transmission X‐ray microscopy to reveal the structural degradation of polymer electrolyte membrane fuel cell catalyst layers due to conditioning and thermal heating of the catalyst coated membrane. We observe a redistribution of the ionomer and carbon‐black in the catalyst layer, as well as nanoscale membrane ...
Spencer Lytle, Harsharaj B. Parmar, Jian Wang, Shohei Yamashita, Aimy Bazylak   +4 more
wiley   +1 more source

Operando Visualization of Cathode Water Management in Proton Exchange Membrane Water Electrolyzers Using Synchrotron X‐Ray Radiography

Advanced Science, EarlyView.
The cathode of proton exchange membrane water electrolyzers remains a poorly understood region despite its importance for hydrogen purity and operational safety. Operando synchrotron X‐ray radiography directly visualizes liquid water behavior and uncovers a transition from continuous to pulsating transport, providing new insight into multiphase ...
Wataru Yoshimune, Tetsuichiro Hayakawa, Yuta Miyase   +2 more
wiley   +1 more source

A TOC na prática: explorando a restrição em uma fábrica

Exacta, 2016
Neste trabalho, desenvolveu-se um modelo teórico para o processo de tomada de decisão de como explorar a restrição de um sistema, baseado na estratégia de planejamento e controle da produção TOC, para sua consequente implementação prática em fábricas com
Ari Franco Romeiro Alves Queiroz, Arinéia Nogueira de Assis, Marco Antonio Figueiredo Menezes, Maria José Pereira Dantas, Moacir Godinho Filho   +4 more
doaj   +1 more source

Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance. [PDF]

PLoS ONE, 2015
Thrombopoietin (Thpo) signals via its receptor Mpl and regulates megakaryopoiesis, hematopoietic stem cell (HSC) maintenance and post-transplant expansion.
Saskia Kohlscheen, Sabine Wintterle, Adrian Schwarzer, Christel Kamp, Martijn H Brugman, Daniel C Breuer, Guntram Büsche, Christopher Baum, Ute Modlich   +8 more
doaj   +1 more source

Real‐Time Monitoring of Mass and Mechanical Properties in Single Cells and Multicellular Spheroids

Advanced Science, EarlyView.
This study introduces photothermally actuated microcantilevers combined with optical microscopy to simultaneously measure morphology, mass, and mechanical properties of cellular systems in real‐time. The findings link cytoplasm‐dominated mechanical energy dissipation to the Q‐factor as a novel biophysical parameter.
Ilaria Incaviglia, Giulia E. M. Ammirati, Sophie Herzog, Tommy Krug, Nico Strohmeyer, Miguel Camacho Rufino, Matthias P. Lutolf, David A. Weitz, Daniel J. Müller   +8 more
wiley   +1 more source