Results 101 to 110 of about 27,223 (192)

Diffusive model of current-in-plane-tunneling in double magnetic tunnel junctions

, 2012
We propose a model that describes current-in-plane tunneling transport in double barrier magnetic tunnel junctions in diffusive regime. Our study shows that specific features appear in double junctions that are described by introducing two typical length
Baraduc, Claire, Chshiev, Mair, Clément, Pierre-Yves, Diény, Bernard, Ducruet, Clarisse   +4 more
core   +4 more sources

Nitrogen-doped mesoporous activated carbon from Lentinus edodes residue: an optimized adsorbent for pharmaceuticals in aqueous solutions

Frontiers in Chemistry
In this study, phosphoric acid activation was employed to synthesize nitrogen-doped mesoporous activated carbon (designated as MR1) from Lentinus edodes (shiitake mushroom) residue, while aiming to efficiently remove acetaminophen (APAP), carbamazepine ...
Bei Chu, Yichen Lou, Yixin Tan, Jiawei Lin, Xingcheng Liu   +4 more
doaj   +1 more source

Targeting pediatric cancers via T-cell recognition of the monomorphic MHC class I-related protein MR1

Journal for ImmunoTherapy of Cancer
Human leukocyte antigen (HLA) restriction of conventional T-cell targeting introduces complexity in generating T-cell therapy strategies for patients with cancer with diverse HLA-backgrounds.
Aimee du Chatinier, Zsolt Sebestyen, Jürgen Kuball, Stefan Nierkens, Anja Krippner-Heidenreich, Yuyan Lu, Ana P Lopes, Ester Dunnebach, Denise A M H van den Beemt, Sebastiaan van Heesch, Annelisa M. Cornel, Loutje van der Sman, Jip T van Dinter, Marta Arrabito, Marliek van Hoesel, Thomas A Kluiver, Noël M M Dautzenberg, Linde Dekker, Jorik M van Rijn, Juliane L Buhl, Farnaz Barneh, Luca Lo Nigro, Esther Hulleman, Jarno Drost, Olaf T Heidenreich, Weng Chuan Peng   +25 more
doaj   +1 more source

Biology of CD1- and MR1-Restricted T Cells

Annual Review of Immunology, 2014
Over the past 15 years, investigators have shown that T lymphocytes can recognize not only peptides in the context of MHC class I and class II molecules but also foreign and self-lipids in association with the nonclassical MHC class I–like molecules, CD1 proteins. In this review, we describe the most recent events in the field, with particular emphasis
Salio, M, Silk, J, Jones, E, Cerundolo, V   +3 more
openaire   +2 more sources

Diverse MR1-restricted T cells in mice and humans

Nature Communications, 2019
Mucosal-associated invariant T (MAIT) cells express invariant TRAV1/TRAJ33 TCR-α gene segments and detect antigens presented by MR1. Here the authors show that atypical, MR1-restricted MAIT populations that include both Trav1+ and Trav1- cells are found ...
Hui-Fern Koay, Nicholas A. Gherardin, Calvin Xu, Rebecca Seneviratna, Zhe Zhao, Zhenjun Chen, David P. Fairlie, James McCluskey, Daniel G. Pellicci, Adam P. Uldrich, Dale I. Godfrey   +10 more
doaj   +1 more source

Rationality of moduli of vector bundles on curves

, 1999
The moduli space M(r,d) of stable, rank r, degree d vector bundles on a smooth projective curve of genus g>1 is shown to be birational to M(h,0) x A, where h=hcf(r,d) and A is affine space of dimension (r^2-h^2)(g-1).
King, A. D., Schofield, A. H.
core  

Diversity and hallmarks of metabolites surveyed by MR1

Immunobiology
Mucosal-associated invariant T (MAIT) cells are one of the innate T cell subset. They are known to contribute to anti-bacterial response by recognizing bacterial components with invariant TCRs which are presented on a monomorphic antigen presenting ...
Emi Ito, Sho Yamasaki
doaj   +1 more source

Cigarette smoke components modulate the MR1–MAIT axis

Journal of Experimental Medicine
Tobacco smoking is prevalent across the world and causes numerous diseases. Cigarette smoke (CS) compromises immunity, yet little is known of the components of CS that impact T cell function. MR1 is a ubiquitous molecule that presents bacterial metabolites to MAIT cells, which are highly abundant in the lungs. Using in silico, cellular, and biochemical
Wael Awad, Jemma R. Mayall, Weijun Xu, Matt D. Johansen, Timothy Patton, Xin Yi Lim, Izabela Galvao, Lauren J. Howson, Alexandra C. Brown, Tatt Jhong Haw, Chantal Donovan, Shatarupa Das, Gesa J. Albers, Tsung-Yu Pai, Elinor Hortle, Caitlin M. Gillis, Nicole G. Hansbro, Jay C. Horvat, Ligong Liu, Jeffrey Y.W. Mak, James McCluskey, David P. Fairlie, Alexandra J. Corbett, Philip M. Hansbro, Jamie Rossjohn   +24 more
openaire   +2 more sources

MHC-related protein 1–restricted recognition of cancer via a semi-invariant TCR-α chain

The Journal of Clinical Investigation
The T cell antigen presentation platform MR1 consists of 6 allomorphs in humans that differ by no more than 5 amino acids. The principal function of this highly conserved molecule involves presenting microbial metabolites to the abundant mucosal ...
Garry Dolton, Hannah Thomas, Li Rong Tan, Cristina Rius Rafael, Stephanie Doetsch, Giulia-Andreea Ionescu, Lucia F. Cardo, Michael D. Crowther, Enas Behiry, Théo Morin, Marine E. Caillaud, Devinder Srai, Lucia Parolini, Md Samiul Hasan, Anna Fuller, Katie Topley, Aaron Wall, Jade R. Hopkins, Nader Omidvar, Caroline Alvares, Joanna Zabkiewicz, John Frater, Barbara Szomolay, Andrew K. Sewell   +23 more
doaj   +1 more source

Regulation of MAIT cells through host-derived antigens

Frontiers in Immunology
Mucosal-associated invariant T (MAIT) cells are a major subset of innate-like T cells that function at the interface between innate and acquired immunity.
Emi Ito, Emi Ito, Emi Ito, Sho Yamasaki, Sho Yamasaki, Sho Yamasaki   +5 more
doaj   +1 more source