Results 101 to 110 of about 8,186 (190)

MR1-074 - Ulau-Suain (wordlist)

open access: yes
A: Ulau-Suain C_remainder (continues from MR1-072 side A) [ written list is MR1-072-suain.pdf] B: (contains no linguistic material).

core   +1 more source

MR1-restricted T cells do not represent a significant population of Mtb-specific T cells in Kb-/-Db-/-M3-/- mice after Mtb infection.

open access: yes, 2016
(A) Lymphocytes isolated from the lungs of Mtb-infected Kb-/-Db-/-M3-/- mice were stimulated with Mtb culture supernatant-pulsed BMDCs from C57BL/6, MR1-/- and β2m-/- mice.
Shaobin Shang (205922)   +4 more
core   +1 more source

Diverse MR1-restricted T cells in mice and humans

open access: yesNature Communications, 2019
Mucosal-associated invariant T (MAIT) cells express invariant TRAV1/TRAJ33 TCR-α gene segments and detect antigens presented by MR1. Here the authors show that atypical, MR1-restricted MAIT populations that include both Trav1+ and Trav1- cells are found ...
Hui-Fern Koay   +10 more
doaj   +1 more source

The MAIT hybridoma response to MR1 mutants.

open access: yes, 2013
(A) The 6C2 MAIT hybridoma was stimulated with mouse MR1 mutants expressed on LM1.8 fibroblasts in the absence (white bars) or presence of bacteria (black bars) at an MOI of 100. The IL-2 response in both cases could be blocked with an anti-MR1 antibody (
James Scott-Browne (104719)   +10 more
core   +1 more source

MR1-070 - Ali sentences

open access: yes
Ali sentences (continued from MR1-069).

core   +1 more source

The regulation of MR1 cell surface expression and antigen presentation

open access: yes, 2021
© 2021 Hui Jing LimMajor histocompatibility complex class I-related protein 1 (MR1) presents vitamin B metabolites that are synthesised by wide range of microbes.
Lim, Hui Jing
core  

Unconventional T cells in anti-cancer immunity

open access: yesFrontiers in Immunology
Unlike conventional T cells that detect peptide antigens loaded to major histocompatibility complex (MHC) molecules, unconventional T cells respond to non-peptidic metabolite antigens presented by MHC class I-like proteins, such as CD1 and MHC-related ...
Ariel Laub   +4 more
doaj   +1 more source

MHC-related protein 1–restricted recognition of cancer via a semi-invariant TCR-α chain

open access: yesThe Journal of Clinical Investigation
The T cell antigen presentation platform MR1 consists of 6 allomorphs in humans that differ by no more than 5 amino acids. The principal function of this highly conserved molecule involves presenting microbial metabolites to the abundant mucosal ...
Garry Dolton   +23 more
doaj   +1 more source

MR1 blockade drives differential impact on integrative signatures based on circuits of circulating immune cells and soluble mediators in visceral leishmaniasis

open access: yesFrontiers in Immunology
IntroductionVisceral leishmaniasis (VL) is an important tropical and neglected disease and represents a serious global health problem. The initial interaction between the phagocytes and the parasite is crucial to determine the pathogen’s capacity to ...
Luana Oliveira Borges-Fernandes   +23 more
doaj   +1 more source

Regulation of MAIT cells through host-derived antigens

open access: yesFrontiers in Immunology
Mucosal-associated invariant T (MAIT) cells are a major subset of innate-like T cells that function at the interface between innate and acquired immunity.
Emi Ito   +5 more
doaj   +1 more source

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