Results 101 to 110 of about 8,186 (190)
MR1-074 - Ulau-Suain (wordlist)
A: Ulau-Suain C_remainder (continues from MR1-072 side A) [ written list is MR1-072-suain.pdf] B: (contains no linguistic material).
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(A) Lymphocytes isolated from the lungs of Mtb-infected Kb-/-Db-/-M3-/- mice were stimulated with Mtb culture supernatant-pulsed BMDCs from C57BL/6, MR1-/- and β2m-/- mice.
Shaobin Shang (205922) +4 more
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Diverse MR1-restricted T cells in mice and humans
Mucosal-associated invariant T (MAIT) cells express invariant TRAV1/TRAJ33 TCR-α gene segments and detect antigens presented by MR1. Here the authors show that atypical, MR1-restricted MAIT populations that include both Trav1+ and Trav1- cells are found ...
Hui-Fern Koay +10 more
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The MAIT hybridoma response to MR1 mutants.
(A) The 6C2 MAIT hybridoma was stimulated with mouse MR1 mutants expressed on LM1.8 fibroblasts in the absence (white bars) or presence of bacteria (black bars) at an MOI of 100. The IL-2 response in both cases could be blocked with an anti-MR1 antibody (
James Scott-Browne (104719) +10 more
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The regulation of MR1 cell surface expression and antigen presentation
© 2021 Hui Jing LimMajor histocompatibility complex class I-related protein 1 (MR1) presents vitamin B metabolites that are synthesised by wide range of microbes.
Lim, Hui Jing
core
Unconventional T cells in anti-cancer immunity
Unlike conventional T cells that detect peptide antigens loaded to major histocompatibility complex (MHC) molecules, unconventional T cells respond to non-peptidic metabolite antigens presented by MHC class I-like proteins, such as CD1 and MHC-related ...
Ariel Laub +4 more
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MHC-related protein 1–restricted recognition of cancer via a semi-invariant TCR-α chain
The T cell antigen presentation platform MR1 consists of 6 allomorphs in humans that differ by no more than 5 amino acids. The principal function of this highly conserved molecule involves presenting microbial metabolites to the abundant mucosal ...
Garry Dolton +23 more
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IntroductionVisceral leishmaniasis (VL) is an important tropical and neglected disease and represents a serious global health problem. The initial interaction between the phagocytes and the parasite is crucial to determine the pathogen’s capacity to ...
Luana Oliveira Borges-Fernandes +23 more
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Regulation of MAIT cells through host-derived antigens
Mucosal-associated invariant T (MAIT) cells are a major subset of innate-like T cells that function at the interface between innate and acquired immunity.
Emi Ito +5 more
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