Results 261 to 270 of about 3,421,970 (401)

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

NONMMUT140591.1 may serve as a ceRNA to regulate Gata5 in UT-B knockout-induced cardiac conduction block

Open Life Sciences, 2021
Lv Xuejiao, Sun Yuxin, Tan Wenxi, Liu Yang, Wen Naiyan, Fu Shuang, Yu Lanying, Liu Tiantian, Qi Xiaocui, Shu Nanqi, Du Yanwei, Zhang Wenfeng, Meng Yan   +12 more
doaj   +1 more source

In-vitro human myogenesis model reveals novel mRNA alternative splicing isoforms. [PDF]

Sci Rep
Donega S, Banskota N, Yang JH, Rossi M, Piao Y, Tsitsipatis D, Fan J, De S, Peterson CA, McDermott MM, Gorospe M, Ferrucci L.   +11 more
europepmc   +1 more source

mRNA vaccines manufacturing: Challenges and bottlenecks

Vaccine, 2021
S. S. Rosa, D. Prazeres, A. Azevedo, M. Marques   +3 more
semanticscholar   +1 more source

Functions of the 5′‐terminal m⁷G cap in eukaryotic mRNA [PDF]

, 1978
Witold Filipowicz
openalex   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

A multivalent mRNA-LNP cocktail vaccine confers superior efficacy against Staphylococcus aureus infection in murine models. [PDF]

NPJ Vaccines
Gao X, Zheng Y, Wang X, Jin J, Liu C, Yang C, Wang PG, He Y.   +7 more
europepmc   +1 more source

Cell‐free synthesis of vesicular stomatitis virus proteins: translation of membrane‐bound polyribosomal mRNAs [PDF]

, 1975
Frances Toneguzzo, Hara P. Ghosh
openalex   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Ocular delivery of lipid nanoparticles-formulated mRNA encoding lanosterol synthase ameliorates cataract in rats. [PDF]

Nat Commun
Song R, Lin Y, Zhang M, Liu Z, Zhang R, Zhao J, Li B.   +6 more
europepmc   +1 more source