Results 111 to 120 of about 5,749,254 (300)

Early changes in rat diaphragm biology with mechanical ventilation [PDF]

, 2003
To better characterize the effects of 24-hour mechanical ventilation on diaphragm, the expression of myogenic transcription factors, myosin heavy chains, and sarcoplasmic/endoplasmic reticulum calcium-ATPase pumps was examined in rats.
Decramer Marc, De Paepe, Kristel, Testelmans, Dries, Cadot Pascal, Gayan-Ramirez Ghislaine, Rácz, Gábor Z., Wuytack, Frank, Rácz Gábor Z., Zádor, Ernő, Decramer, Marc, Testelmans Dries, Paepe De Kristel, Cadot, Pascal, Zádor Ernő, Wuytack Frank, Gayan-Ramirez, Ghislaine   +15 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Molecular implications of prolonged aggression experience: Th, Dat1, Snca and Bdnf gene expression in the ventral tegmental area of the victorious male mice [PDF]

, 2008
Th, Dat1, Snca and Bdnf were the genes whose mRNA levels in the ventral tegmental area of the midbrain were measured in male mice that were victorious in 20 daily agonistic interactions and in a group of such victorious mice that had later not been ...
I. L. Kovalenko, Irina L. Kovalenko, U. A. Boyarskikh, M. L. Filipenko, Ul'yana A. Boyarskikh, N. N. Kudryavtseva, N. P. Bondar, Maxim L. Filipenko, Natalia P. Bondar, Natalia N. Kudryavtseva   +9 more
core  

siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway

Cancer Management and Research, 2019
Yini Ma,1,2 Liying Guan,1 Yanxin Han,1 Yi Zhou,1 Xiaoming Li,1 Yumei Liu,1 Xiujuan Zhang,1 Weiying Zhang,1 Xiaohong Li,1 Shuhua Wang,1 Weidong Lu11Health Management Center, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021 ...
Ma Y, Guan L, Han Y, Zhou Y, Li X, Liu Y, Zhang X, Zhang W, Li X, Wang S, Lu W   +10 more
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Distribution of wildtype CAP2/Tmprss4 mRNA transcript expression.

, 2015
CAP2/Tmprss4 mRNA expression profile in WT mice (n = 4) in various organs as indicated; individual values were normalized to β-actin.
Sumedha Malsure (788164), Qing Wang (27728), Ditte Andreasen (788161), Antoine Nobile (788165), Edith Hummler (138682), Anne-Marie Mérillat (521931), Anna Keppner (788160), Julie Bapst (788162), Marc Maillard (93048), Camille Ansermet (788163)   +9 more
core   +1 more source

Expression Profile of Hyaluronidase mRNA Transcripts in the Kidney and in Renal Cells

Kidney and Blood Pressure Research, 1998
The accumulation of hyaluronan (HA) in the renal cortex is a characteristic feature of inflammatory renal diseases. Fragments of HA derived from high molecular weight precursors are known to display inflammatory effects in vitro and could, therefore, participate in immune renal injury.
Sun L, Feusi E, Sibalic A, Beck-Schimmer B, Wüthrich RP   +4 more
openaire   +3 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

mRNA expression by cDNA arrays.

, 2015
(A), Whole-genome mRNA profile and extraction of c-Myc (B) and CNND2 (C), and the related genes followed the same pathways in ES cells and hMSCs. The color bar represents the grades of the relative expression levels; red color indicates an increase ...
Masanori Kawano (798368), Ichiro Itonaga (798369), Kazuhiro Tanaka (434060), Tatsuya Iwasaki (798370), Hiroshi Tsumura (798371)   +4 more
core   +1 more source