Results 81 to 90 of about 5,749,254 (300)

In silico analysis of GPAT2 mRNA expression profile.

open access: yes, 2014
A) In silico analysis of GPAT2 expression profile across human normal tissues. B) GPAT2 mRNA expression across different tumor localizations was assessed with a bioinformatics approach, and expression level was classified into low, moderate and high. The
Mercedes C. Soler-Gerino (589259)   +9 more
core   +1 more source

Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. [PDF]

open access: yes, 2010
Kaposi's sarcoma (KS) is the most common cancer among HIV-positive patients. Histogenetic origin of KS has long been elusive due to a mixed expression of both blood and lymphatic endothelial markers in KS tumor cells.
Kafka, Darren   +37 more
core   +1 more source

The Role of Regulated mRNA Stability in Establishing Bicoid Morphogen Gradient in Drosophila Embryonic Development [PDF]

open access: yes, 2011
The Bicoid morphogen is amongst the earliest triggers of differential spatial pattern of gene expression and subsequent cell fate determination in the embryonic development of Drosophila.
Niranjan Mahesan   +5 more
core   +3 more sources

Identification of key modules and hub genes involved in regulating the feather follicle development of Wannan chickens using WGCNA

open access: yesPoultry Science
: Carcass appearance is important economic trait, which affects customers in making purchase decisions. Both density and diameter of feather follicles are two important indicators of carcass appearance.
Jiangxian Wang   +8 more
doaj   +1 more source

HnRNP Q Has a Suppressive Role in the Translation of Mouse Cryptochrome1. [PDF]

open access: yesPLoS ONE, 2016
Precise regulation of gene expression is especially important for circadian timekeeping which is maintained by the proper oscillation of the mRNA and protein of clock genes and clock-controlled genes. As a main component of the core negative arm feedback
Ilgye Lim   +3 more
doaj   +1 more source

Expression profile of mRNAs from human pancreatic islet tumors [PDF]

open access: yesJournal of Molecular Endocrinology, 2003
Abstract In order to understand the tIssue specificity of the endocrine pancreas, it is important to clarify the expression profile of mRNAs in various states of the tIssue. A total of approximately 9000 non-redundant expressed genes from human pancreatic islets and insulinoma have so far been determined as expressed sequence tags ...
L, Jin   +8 more
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ Signaling.

open access: yesPLoS ONE, 2016
Uptake of Ca2+ into the mitochondrial matrix controls cellular metabolism and survival-death pathways. Several genes are implicated in controlling mitochondrial Ca2+ uptake (mitochondrial calcium regulatory genes, MCRGs), however, less is known about the
Nóra M Márkus   +8 more
doaj   +1 more source

Biologically relevant effects of mRNA amplification on gene expression profiles [PDF]

open access: yesBMC Bioinformatics, 2006
Abstract Background Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies and/or needle biopsies from human or animal tissues.
van Haaften, Rachel I. M.   +9 more
openaire   +5 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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