Results 131 to 140 of about 2,567 (167)
Unraveling the landscape of non-melanoma skin cancer through single-cell RNA sequencing technology. [PDF]
Front OncolYan G, Wang X, Zhang G.
europepmc +1 more source
Red panda intestinal organoids for the functional analysis of <i>Lactobacillus salivarius</i>. [PDF]
iScienceGuo Q +11 more
europepmc +1 more source
Arabidopsis MSI1 connects LHP1 to PRC2 complexes [PDF]
EMBO Journal, 2013 Polycomb group (PcG) proteins form essential epigenetic memory systems for controlling gene expression during development in plants and animals. However, the mechanism of plant PcG protein functions remains poorly understood. Here, we probed the composition and function of plant Polycomb repressive complex 2 (PRC2).
Maria Derkacheva +2 more
exaly +5 more sources
Msi1-Like (MSIL) Proteins in Fungi [PDF]
Mycobiology, 2013 Msi1-like (MSIL) proteins, which are eukaryote-specific and contain a series of WD40 repeats, have pleiotropic roles in chromatin assembly, DNA damage repair, and regulation of nutrient/stress-sensing signaling pathways. In the fungal kingdom, the functions of MSIL proteins have been studied most intensively in the budding yeast model Saccharomyces ...
Yong-Sun Bahn
exaly +3 more sources
Arabidopsis MSI1 Is Required for Negative Regulation of the Response to Drought Stress [PDF]
Molecular Plant, 2009 Arabidopsis MSI1 has fundamental functions in plant development. MSI1 is a subunit of Polycomb group protein complexes and Chromatin assembly factor 1, and it interacts with the Retinoblastoma-related protein 1. Altered levels of MSI1 result in pleiotropic phenotypes, reflecting the complexity of MSI1 protein functions.
Yvonne Steinbach +2 more
exaly +3 more sources
Strategic Decoy Peptides Interfere with MSI1/AGO2 Interaction to Elicit Tumor Suppression Effects [PDF]
Cancers, 2022 Peptide drugs that target protein–protein interactions have attracted mounting research efforts towards clinical developments over the past decades. Increasing reports have indicated that expression of Musashi 1 (MSI1) is tightly correlated to high grade of cancers as well as enrichment of cancer stem cells.
Liang-Ting Lin, Yi-Wei Chen, Pin-I Huang
exaly +3 more sources
The Musashi proteins MSI1 and MSI2 are required for photoreceptor morphogenesis and vision in mice [PDF]
Journal of Biological Chemistry, 2021 The Musashi family of RNA-binding proteins is known for its role in stem-cell renewal and is a negative regulator of cell differentiation. Interestingly, in the retina, the Musashi proteins MSI1 and MSI2 are differentially expressed throughout the cycle of retinal development, with MSI2 protein displaying robust expression in the adult retinal tissue ...
Fatimah Matalkah +2 more
exaly +3 more sources