Results 11 to 20 of about 156,870 (288)
Does Human mtDNA Recombine? [PDF]
In this article we review the evidence for and against recombination in human mtDNA. If recombination occurs, there needs to be a route by which genetic material can incorporate itself into the mitochondrial genome, and hence between mitochondrial lineages.
A, Eyre-Walker, P, Awadalla
openaire +2 more sources
Transmission of mitochondrial DNA following assisted reproduction and nuclear transfer [PDF]
Review of the articleMitochondria are the organelles responsible for producing the majority of a cell's ATP and also play an essential role in gamete maturation and embryo development.
Alam +200 more
core +2 more sources
Regulated mitochondrial DNA replication during oocyte maturation is essential for successful porcine embryonic development. [PDF]
Cellular ATP is mainly generated through mitochondrial oxidative phosphorylation, which is dependent on mitochondrial DNA (mtDNA). We have previously demonstrated the importance of oocyte mtDNA for porcine and human fertilization.
Alexander, Jan +26 more
core +6 more sources
No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis [PDF]
BACKGROUND: Mitochondrial dysfunction is an established feature of multiple sclerosis (MS). We recently described high levels of mitochondrial DNA (mtDNA) deletions within respiratory enzyme-deficient (lacking mitochondrial respiratory chain complex IV ...
Abadi A +36 more
core +2 more sources
Stable genetic structure and connectivity in pollution-adapted and nearby pollution-sensitive populations of Fundulus heteroclitus [PDF]
Populations of the non-migratory estuarine fish Fundulus heteroclitus inhabiting the heavily polluted New Bedford Harbour (NBH) estuary have shown inherited tolerance to local pollutants introduced to their habitats in the past 100 years. Here we examine
Joaquin C. B. Nunez +6 more
doaj +1 more source
Background. Despite the study of the variability of the mtDNA control region of the esternimperial eagles in the Volga population, due attention was not paid to cyt b, the second mitochondrial marker.
M.D. Simakov +3 more
doaj +1 more source
Molecular Analysis of Mazandrani native chicken population based on HVR-I region of Mitochondrial DNA [PDF]
Reserving genetic diversity in native chicken breeds of Iran because of little population size is necessary for breeding goals and increasing their production. The first step is determination of genetic diversity in existing populations.
Nasrollah Pirani +2 more
doaj +1 more source
Site-specific selection reveals selective constraints and functionality of tumor somatic mtDNA mutations. [PDF]
BACKGROUND: Previous studies have indicated that tumor mitochondrial DNA (mtDNA) mutations are primarily shaped by relaxed negative selection, which is contradictory to the critical roles of mtDNA mutations in tumorigenesis.
Chen, Cheng +10 more
core +2 more sources
Melanesian populations are known for their diversity, but it has been hard to grasp the pattern of the variation or its underlying dynamic. Using 1,223 mitochondrial DNA (mtDNA) sequences from hypervariable regions 1 and 2 (HVR1 and HVR2) from 32 populations, we found the among-group variation is structured by island, island size, and also by language ...
Jonathan S Friedlaender +9 more
openaire +7 more sources
The interpretation of a signal sent by the mtDNA cytb gene as a molecular marker in phylogenetic and population genetic research can be complicated by cumulative influence of parallel mutations, i.e., the entropy of nucleotide sequences.
A. G. Lapinski +3 more
doaj +1 more source

