Mitochondrial dysfunction at the cornerstone of inflammatory exacerbation in aged macrophages
Immunosenescence encompasses multiple age-related adaptations that result in increased susceptibility to infections, chronic inflammatory disorders, and higher mortality risk.
Rafael Moura Maurmann +3 more
doaj +1 more source
Telomere Length as a Marker of Suicidal Risk in Schizophrenia [PDF]
BACKGROUND: Schizophrenia and suicidal behavior are associated with shortening in the length of telomeres. The aim of the study was to compare the content (pg/mcg) of telomeric repeat in DNA isolated from peripheral blood cells in three groups of ...
Natalia V. Zakharova +7 more
doaj +1 more source
Phylogeography of Calomyscus elburzensis (Calomyscidae, Rodentia) around the Central Iranian Desert with Description of a New Subspecies in Center of Iranian Plateau [PDF]
Calomyscus elburzensis Goodwin, 1938, was previously known from central and northern Iran to southern and southwestern Turkmenistan and northwestern Afghanistan.
S. Akbarirad, J. Darvish, M. Aliabadian
doaj
mtDNA-CN measured across DNA extraction methods.
mtDNA-CN measured by qPCR was mean-zeroed and averaged across three runs for Lyse, PCIAA and Qiagen Kit DNA extractions. Variance for Lyse, PCIAA and Qiagen Kit are 0.02, 0.17 and 0.59 respectively. PCIAA, phenol:chloroform:isoamyl alcohol.
Jason A. Sumpter (8384526) +12 more
core +1 more source
A critical reassessment of the role of mitochondria in tumorigenesis [PDF]
<p><b>Background:</b> Mitochondrial DNA (mtDNA) is being analyzed by an increasing number of laboratories in order to investigate its potential role as an active marker of tumorigenesis in various types of cancer.
Bandelt, H.J. +23 more
core +1 more source
Global patterns in human mitochondrial DNA and Y-chromosome variation caused by spatial instability of the local cultural processes [PDF]
Because of the widespread phenomenon of patrilocality, it is hypothesized that Y-chromosome variants tend to be more localized geographically than those of mitochondrial DNA ( mtDNA).
Reddy, B. Mohan +37 more
core +3 more sources
mtDNA-CN in psoriasis patients and healthy controls.
The mtDNA-CN was quantified by real-time qPCR in peripheral blood buffy coat samples from patients with psoriasis (n = 56) and healthy controls (n = 44). A: Bar graph of data expressed as the mean ± standard deviation (SD). B: Dot plot of data.
Suad AlFadhli (477959) +2 more
core +1 more source
The complete mitochondrial genomes were sequenced from three individuals of the endemic charr Salvelinus sp. 4 [ from Lake Nachikinskoe (Kamchatka, Russia). The complete mitochondrial genomes were 16,654 bp in size; the genome organization and GC content
Alla G. Oleinik +2 more
doaj +1 more source
Genotyping human ancient mtDNA control and coding region polymorphisms with a multiplexed Single-Base-Extension assay: the singular maternal history of the Tyrolean Iceman [PDF]
Background Progress in the field of human ancient DNA studies has been severely restricted due to the myriad sources of potential contamination, and because of the pronounced difficulty in identifying authentic results.
Endicott, Phillip +31 more
core +1 more source

