Results 61 to 70 of about 166,442 (338)
Journal of Bioinformatics and Genomics, 2023 A retrospective analysis of the theoretical developments of the causes of the phenomenon of heterosis has been carried out. In connection with new scientific achievements of the fundamental sciences, various hypotheses of heterosis have been revised.
Bekenev, V.A.
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Ethics of modifying the mitochondrial genome [PDF]
, 2010 Recent preclinical studies have shown the feasibility of specific variants of nuclear transfer to prevent mitochondrial DNA disorders. Nuclear transfer could be a valuable reproductive option for carriers of mitochondrial mutations.
Bredenoord, A L +3 more
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Advanced Functional Materials, EarlyView.A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
The mitochondrial genome of the endemic Brazilian paradoxical frog Pseudis tocantins (Hylidae)
Mitochondrial DNA. Part B. Resources, 2018 In this work, we present for the first time the mitochondrial genome of a paradoxical frog (Pseudis tocantins). This genome is 15.56 kb, excluding the control region, and is similar in gene content to other hylid mitogenomes. Maximum likelihood analysis,
Kaleb Pretto Gatto +2 more
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Mitochondrial DNA. Part B. Resources, 2020 Coregonid fishes are among the most successful groups in the subarctic, boreal, and subalpine fresh waters of the northern hemisphere. Limnetic–benthic sympatric species-pairs from two different evolutionary lineages, the North American lake whitefish ...
Veronika Teterina +9 more
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Mitochondria directly influence fertilisation outcome in the pig [PDF]
, 2006 The mitochondrion is explicitly involved in cytoplasmic regulation and is the cell's major generator of ATP. Our aim was to determine whether mitochondria alone could influence fertilisation outcome.
Abeydeera +66 more
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Advanced Functional Materials, EarlyView.The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang +13 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2017 The complete mitochondrial genome of an undescribed gnomefish species of the genus Scombrops was determined using a PCR-based method. The total length of mitochondrial DNA (mtDNA) was 16,521 bp, and included 13 protein-coding genes, two ribosomal RNA ...
Yukako Mochizuki +7 more
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Mitochondrial DNA. Part B. Resources, 2020 In this study, we analyzed the complete mitochondrial genome sequence of the hawk moth, Theretra oldenlandiae. The complete mitogenome sequence of T. oldenlandiae was observed to be a circular molecule 15,312 bp long and consisting of 13 protein-coding ...
Xu Wang +3 more
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CHEMERIN AS A POTENTIAL REGULATOR OF MITOCHONDRIAL QUALITY CONTROL IN OBESE PATIENTS
Медицинская иммунология, 2021 In obese patients, the relationship between the content of chemerin in blood plasma and the expression of genes TFAM, Drp1, MFN2, SOD, BAX, responsible for quality control of mitochondria, in insulin-dependent tissues (adipose tissue, liver) was revealed.
M. A. Vulf +7 more
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