Results 71 to 80 of about 156,870 (288)
Mitochondrial DNA. Part B. Resources, 2020 Coregonid fishes are among the most successful groups in the subarctic, boreal, and subalpine fresh waters of the northern hemisphere. Limnetic–benthic sympatric species-pairs from two different evolutionary lineages, the North American lake whitefish ...
Veronika Teterina +9 more
doaj +1 more source
Transmitochondrial embryonic stem cells containing pathogenic mtDNA mutations are compromised in neuronal differentiation [PDF]
, 2009 Objectives: Defects of the mitochondrial genome (mtDNA) cause a series of rare, mainly neurological disorders. In addition, they have been implicated in more common forms of movement disorders, dementia and the ageing process.
Acin-Perez, Rebecca +8 more
core +2 more sources
Frontiers in AgingAging is the major risk factor in most of the leading causes of mortality worldwide, yet its fundamental causes mostly remain unclear. One of the clear hallmarks of aging is mitochondrial dysfunction. Mitochondria are best known for their roles in cellular energy generation, but they are also critical biosynthetic and signaling organelles.
Sprason, Charlotte +2 more
openaire +3 more sources
Advanced Science, EarlyView.Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li +8 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2017 The complete mitochondrial genome of an undescribed gnomefish species of the genus Scombrops was determined using a PCR-based method. The total length of mitochondrial DNA (mtDNA) was 16,521 bp, and included 13 protein-coding genes, two ribosomal RNA ...
Yukako Mochizuki +7 more
doaj +1 more source
Mitochondrial DNA. Part B. Resources, 2020 In this study, we analyzed the complete mitochondrial genome sequence of the hawk moth, Theretra oldenlandiae. The complete mitogenome sequence of T. oldenlandiae was observed to be a circular molecule 15,312 bp long and consisting of 13 protein-coding ...
Xu Wang +3 more
doaj +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
Advanced Science, EarlyView.The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2019 The northern anchovy, Engraulis mordax, is a small planktivorous fish from the northeastern Pacific Ocean that is an important forage for fishes, birds, and marine mammals, and is also the target of a commercial fishery.
Olivia H. Lewis, Sean C. Lema
doaj +1 more source
Uncovering the sources of DNA found on the Turin Shroud [PDF]
, 2015 The Turin Shroud is traditionally considered to be the burial cloth in which the body of Jesus Christ was wrapped after his death approximately 2000 years ago.
Achilli, Alessandro +4 more
core +1 more source
Molecular Therapy - Methods & Clinical DevelopmentMitochondrial DNA (mtDNA) analysis is crucial for the diagnosis of mitochondrial disorders, forensic investigations, and basic research. Existing pipelines are complex, expensive, and require specialized personnel. In many cases, including the diagnosis of detrimental single nucleotide variants (SNVs), mtDNA analysis is still carried out using Sanger ...
Dobner, Jochen +7 more
openaire +4 more sources