Results 41 to 50 of about 26,586 (174)
, 2015 Overview of prevalence (ref 6) and specific enzyme activity in vitro (ref 7) for various genotypes of MTHFR in healthy individuals, based on combinations of the polymorphisms C677T and A1298C.Genotypes of MTHFR.
Michael Matousek (202832) +6 more
core +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina +7 more
wiley +1 more source
The role of the MTHFR gene in migraine
, 2012 Migraine is a common neurological disorder and is characterized by debilitating head pain and an assortment of additional symptoms which can include nausea, emesis, photophobia, phonophobia, and occasionally, visual sensory disturbances.
Stuart, Shani +6 more
core +1 more source
Maternal &Child Nutrition, EarlyView.ABSTRACT Neural tube defects (NTDs) are severe birth defects linked to insufficient maternal folate status during early pregnancy. Red blood cell (RBC) folate concentration is the recommended biomarker for predicting NTD risk, with a threshold of 748 nmol/L using the US Centers for Disease Control and Prevention (CDC) microbiological assay. However, in
Biniyam Tesfaye +5 more
wiley +1 more source
No Association Between MTHFR A1298C and MTRR A66G Polymorphisms, and MS in an Australian Cohort [PDF]
, 2007 Multiple sclerosis (MS) is a complex neurological disease that affects the central nervous system (CNS) resulting in debilitating neuropathology. Pathogenesis is primarily defined by CNS inflammation and demyelination of nerve axons.
Tajouri, Lotti +19 more
core +1 more source
Association of Methylenetetrahydrofolate Reductase (MTHFR-677 and MTHFR-1298) Genetic Polymorphisms with Occlusive Artery Disease and Deep Venous Thrombosis in Macedonians [PDF]
, 2008 Cilj Ispitati moguću povezanost genetičkog polimorfizma metilen-tetrahidrofolatne reduktaze (MTHFR-677, MTHFR-1298) s okluzivnom arterijskom bolešću i dubokom venskom trombozom u Makedonaca.
Krstevska, Marija +11 more
core +1 more source
Arthritis Care &Research, Volume 78, Issue 11, Page 1691-1700, November 2026.Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli +10 more
wiley +1 more source
, 2023 Methylenetetrahydrofolatereductase (MTHFR) is an enzyme that plays a significant role in methylation— one of the most important metabolic pathways in the human body.
Hedger, Laura E
core
Pteridines, 2019 Objective: The aim of this study was to investigate the methylenetetrahydrofolate reductase (MTHFR) gene rs1801133 C>T polymorphisms and lung cancer susceptibility by pooling openly published data.
Liu Fang +6 more
doaj +1 more source
Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.ABSTRACT Nutritional therapy is critical in managing inherited metabolic diseases (IMDs), and includes specialized diets and single nutritional therapy products (sNTPs) such as vitamins, cofactors, and amino acids. Many sNTPs function as medicines, but are regulated as food (e.g., food supplements), which can limit access, reimbursement, and consistent
Nina N. Stolwijk +39 more
wiley +1 more source