Results 221 to 230 of about 75,068 (344)

Brain metastasis in non‐small cell lung cancer: High‐risk factors and predictive models

VIEW, EarlyView.
Artificial intelligence (AI) can integrate of data to predict brain metastases (BM) in non‐small cell lung cancer (NSCLC). AI algorithms are employed to analyze these multifaceted datasets, enabling the identification of complex patterns and correlations that may not be apparent through traditional analytical methods.
Chen Gong, Ben Zhao, Shuangshuang Mao, Qingxu Liu, Yuanyuan Zhao, Yiwen Liu, Yao Luo, Qianxia Li   +7 more
wiley   +1 more source

The Rheb-mTORC1 Coordinates Cell Cycle Progression and Endoreplication in <i>Bombyx mori</i>. [PDF]

Insects
Tang Z, Liu H, Liu Q, Tang X, Xu J, Luo G, Xia Q, Zhao P.   +7 more
europepmc   +1 more source

Faculty Opinions recommendation of Pregnancy restores the regenerative capacity of the aged liver via activation of an mTORC1-controlled hyperplasia/hypertrophy switch.

, 2010
Joseph Avruch, Angela Papageorgiou
openalex   +1 more source

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB [PDF]

, 2012
José A. Martina, Yong Chen, Marjan Guček, Rosa Puertollano   +3 more
openalex   +1 more source

Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth

Nature Chemical Biology, 2021
Bianca J. Lee, Jacob A Boyer, G. Burnett, Arun P. Thottumkara, N. Tibrewal, Stacy L. Wilson, Tientien Hsieh, Abby Marquez, Edward G. Lorenzana, James W. Evans, Laura Hulea, G. Kiss, Hui Liu, Dong Lee, O. Larsson, Shannon Mclaughlan, I. Topisirovic, Zhengping Wang, Zhican Wang, Yongyuan Zhao, D. Wildes, James B Aggen, Mallika Singh, Adrian L Gill, J. Smith, N. Rosen   +25 more
semanticscholar   +1 more source

Different parts of the mussel Gigantidas haimaensis holobiont responded differently to deep‐sea sampling stress

Integrative Zoology, EarlyView.
Symbiotic gill and nonsymbiotic mantle of mussel Gigantidas haimaensis responded differently to deep‐sea sampling stress caused by acute environmental changes. Sharply increased transcription factors potentially play key roles in initiating the response of sampled deep‐sea macrobenthos to the sampling stress.
Guoyong YAN, Tong WEI, Yi LAN, Ting XU, Peiyuan QIAN   +4 more
wiley   +1 more source

Muscle-specific AXIN1 and AXIN2 double knockout does not alter AMPK/mTORC1 signalling or glucose metabolism. [PDF]

J Physiol
Persson KW, Meneses-Valdés R, Andersen NR, Pedersen FS, Gallero S, Hesselager SA, Henriquez-Olguin C, Jensen TE.   +7 more
europepmc   +1 more source

mTORC1 Links Protein Quality and Quantity Control by Sensing Chaperone Availability

, 2010
Shu Bing Qian, Xingqian Zhang, Jun Sun, Jack R. Bennink, Jonathan W. Yewdell, Cam Patterson   +5 more
openalex   +2 more sources

Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway [PDF]

, 2012
Jung Min Han, Seung Jae Jeong, Min‐Chul Park, Gyuyoup Kim, Nam Hoon Kwon, Hoi Kyoung Kim, Sang Hoon Ha, Sung Ho Ryu, Sung‐Hoon Kim   +8 more
openalex   +1 more source

Rapamycin, Not Metformin, Mirrors Dietary Restriction‐Driven Lifespan Extension in Vertebrates: A Meta‐Analysis

Aging Cell, EarlyView.
The authors provide evidence that, together with Dietary Restriction, Rapamcyin and not Metformin, provides a significant lifespan extension in vertebrates. ABSTRACT Dietary restriction (DR) robustly increases lifespan across taxa. However, in humans, long‐term DR is difficult to maintain, leading to the search for compounds that regulate metabolism ...
Edward R. Ivimey‐Cook, Zahida Sultanova, Alexei A. Maklakov   +2 more
wiley   +1 more source