Results 211 to 220 of about 66,391 (264)

Cooperative inhibition of mTORC1 disrupts iron-redox homeostasis and triggers ferritinophagy-dependent ferroptosis in hepatocellular carcinoma. [PDF]

Redox Biol
Chen X, Tan Z, Zhao S, Li F, Liu Y, Ren C, Li J, Lo H, Cui Y, Zhou A, Zhu C, Wu A, Jiang N, Ren F.   +13 more
europepmc   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

Journal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur, Kinga Grzech‐Leśniak, Samuel F. Suslavich, Janina Golob Deeb   +3 more
wiley   +1 more source

Global cellular responses to lysosomal damage. [PDF]

Curr Biol
Jia J.
europepmc   +1 more source

Effects of essential amino acids on phagostimulation and reproduction in adults of the Mediterranean fruit fly Efectos de amino ácidos esenciales en la fago‐estimulación y reproducción en adultos de la mosca de las frutas del Mediterráneo

Physiological Entomology, EarlyView.
The phagostimulation and reproductive effects of individual essential amino acids, without other nutrient except fructose, were investigated. Methionine, Arginine and Leucine display significantly higher phagostimulation strength than fructose. Arginine and Methionine showed a significant improvement in reproductive activity compared to other tested ...
David Nestel, Eleni Verykouki, Santiago J. Aguirre‐Ibáñez, Martha N. Guillen‐Rivera, Carlos Pascacio‐Villafán, Polychronis Rempoulakis, M. Teresa Vera   +6 more
wiley   +1 more source

Short-chain fatty acids act as metabolic and epigenetic regulators in CAR T cell therapy. [PDF]

Mol Ther Oncol
Ma MY, Zhou CX, Shi XY, Zhu JM, Duan CW.
europepmc   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Nomilin Rewires mTOR-Driven Immunometabolism via DDIT4 to Restrain Psoriasis. [PDF]

Int J Biol Sci
Kim HE, Lee ST, Park HS, Lee HS, Lee JY, Kim DK, Roh SG, Nam KH, Kim SH, Choi JK.   +9 more
europepmc   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Is Nuclear mTOR Relevant for Neuronal Dysfunction? [PDF]

J Neurochem
Kumari S, Pagano R, Orzol K, Jaworski J.
europepmc   +1 more source