Results 221 to 230 of about 66,391 (264)

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Amino-acids-mTORC1-driven DDA1 phosphorylation promotes DNA repair and glioblastoma progression. [PDF]

Cell Commun Signal
Chen X, Wang Z, Yan A, Liu Y, Zhu R, Li L, Xu D, Liu R, Zhan X, Yin B, Han W, Peng X.   +11 more
europepmc   +1 more source

Targeting mTOR in Systemic Lupus Erythematosus: From Immune Cell Dysfunction to Clinical Translation. [PDF]

J Inflamm Res
Jiang X, Sun L, Ji J, Zhao C, Wang Y, Zhang H, Wu Q, Su Q, Li F, Zhang S, Cheng T.   +10 more
europepmc   +1 more source

Orchestration of Autophagy and Senescence: Kinases Take the Center Stage. [PDF]

Cells
Basu A.
europepmc   +1 more source

Farnesyl Transferase Inhibitor KO-2806 (Darlifarnib) Enhances the Antitumor Activity of Tyrosine Kinase Inhibitors in RCC. [PDF]

Mol Cancer Ther
Gasendo JG, Chan S, Patel HV, Smith AE, Kessler L, Liu YA, Mitra A, Burrows F, Malik S.   +8 more
europepmc   +1 more source

Mitochondria-sarcoplasmic reticulum crosstalk as a modulator of skeletal muscle mass. [PDF]

J Physiol Biochem
Casuso RA.
europepmc   +1 more source

TOMM40/FADS2 Expression Ratio Predicts the Sensitivity to mTOR Inhibitors in Triple-Negative Breast Cancer. [PDF]

Cancer Med
Farah SM, Zheng JQ, Lee LT, Lu HW, Wang WK, Kuei CH, Lin HY, Chiu HW, Lin YF.   +8 more
europepmc   +1 more source

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Limiting mTORC1

Science Signaling, 2013
A protein complex identified as a negative regulator of the mTORC1 protein kinase complex has tumor suppressor functions.
openaire   +2 more sources