Results 261 to 270 of about 103,930 (303)

Regulatory role of mTORC1 signaling in osteoblasts in acute myeloid leukemia progression and steady-state hematopoiesis. [PDF]

iScience
Fukasawa K, Tokumura K, Yoshimoto M, Sadamori K, Mosialou I, Harakawa Y, Isawa K, Tsuji S, Inufusa H, Hirao A, Kousteni S, Hinoi E.   +11 more
europepmc   +1 more source

The oncogenic signalosome: SQSTM1/p62 as a master integrator of signaling, metabolism, and autophagy in cancer. [PDF]

Toxicol Res
Choi EJ, Jeon SM.
europepmc   +1 more source

Branched-chain amino acids and insulin resistance in type 2 diabetes: from metabolic dysregulation to therapeutic targets. [PDF]

Front Endocrinol (Lausanne)
Mei J, Yang FY, Gong Q.
europepmc   +1 more source

Acute Cold Exposure Cell-Autonomously Reduces mTORC1 Signaling and Protein Synthesis Independent of AMPK. [PDF]

Cells
Sung BY, Ford EJ, Foster DJ, Fullmer KJ, Cromwell C, Viollet B, Thomson DM.   +6 more
europepmc   +1 more source

Low-dose galactose rebalances HBP-mTORC1-SREBP-1c signaling to suppress hepatic lipogenesis and protect against early-stage alcohol-related liver disease. [PDF]

Am J Physiol Gastrointest Liver Physiol
Li Y, Guo R, Qian Y, Hawro I, Cordoba-Chacon J, Jiang Y, Song Z.   +6 more
europepmc   +1 more source

Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.

Elife
Carroll B, Maetzel D, Maddocks ODK, Otten G, Ratcliff M, Smith GR, Dunlop EA, Passos JF, Davies OR, Jaenisch R, Tee AR, Sarkar S, Korolchuk VI.   +12 more
europepmc   +1 more source

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Limiting mTORC1

Science Signaling, 2013
A protein complex identified as a negative regulator of the mTORC1 protein kinase complex has tumor suppressor functions.
openaire   +2 more sources

Seeing mTORC1 specificity

Science, 2016
Structural information reveals how a multiprotein complex responds to amino acid abundance [Also see Research Articles by Wolfson et al. and Aylett et al. and
Gwen R. Buel, John Blenis
openaire   +1 more source