Results 271 to 280 of about 102,812 (293)

<i>Leishmania</i> mediated regulation of host metabolism: impact on host immunity. [PDF]

Front Immunol
Onwah SS, Gupta G, Zayats R, Banga AS, Chottaria K, Ahluwalia G, Uzonna JE.   +6 more
europepmc   +1 more source

mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review). [PDF]

Int J Mol Med
Huo R, Yang Y, Wei C, Yang Y, Meng D, Lin J, Huang X.   +6 more
europepmc   +1 more source

ASS1 facilitates T-ALL progression via the arginine-mediated mTORC1/c-Myc signaling pathway. [PDF]

Sci Rep
Zhang Z, Liu X, Wu Q, Liang J, Zhao Y, Deng J, Wang Y, Yu Q, Ye Z, Zhu H, Lin J.   +10 more
europepmc   +1 more source

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Limiting mTORC1

Science Signaling, 2013
A protein complex identified as a negative regulator of the mTORC1 protein kinase complex has tumor suppressor functions.
openaire   +2 more sources

Seeing mTORC1 specificity

Science, 2016
Structural information reveals how a multiprotein complex responds to amino acid abundance [Also see Research Articles by Wolfson et al. and Aylett et al. and
Gwen R. Buel, John Blenis
openaire   +1 more source

MTORC1-dependent reprogramming

Science Signaling, 2020
DDIT4 and IFRD1 trigger the inhibition and reactivation of MTORC1 during regenerative repair.
openaire   +1 more source

Lysosomal cholesterol activates mTORC1

Science, 2017
Cholesterol Sensing The mTORC1 kinase is a master nutrient sensor that governs cellular metabolism. When dysregulated, this kinase drives several human diseases, including cancer and diabetes. Recent work has delineated a pathway through which amino acids regulate mTORC1.
openaire   +2 more sources