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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
Cell, 2021Mirja Tamara Prentzell +2 more
exaly
Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
Cell, 2021Charles L Evavold +2 more
exaly
2009
mTORC1 is an important regulator of cell growth and cell proliferation and its activity is adjusted in response to multiple cues including oxygen levels. Under conditions of hypoxia, mTORC1 is inhibited. Hypoxia-induced mTORC1 inhibition typically involves the REDD1 protein.
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mTORC1 is an important regulator of cell growth and cell proliferation and its activity is adjusted in response to multiple cues including oxygen levels. Under conditions of hypoxia, mTORC1 is inhibited. Hypoxia-induced mTORC1 inhibition typically involves the REDD1 protein.
openaire +1 more source
mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding
Cell, 2018Morgan Delarue +2 more
exaly
A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma
Cancer Cell, 2017Ozlem Aksoy +2 more
exaly