Results 91 to 100 of about 4,722 (199)

Biochemical and structural mechanisms of multidrug efflux pump transcription regulators, Neisseria gonorrhoeae MtrR and Escherichia coli MprA

open access: yes, 2021
As bacterial resistance to multiple antibiotics continues to become a growing problem across the globe, the imperativeness for understanding mechanisms of antibiotic and multidrug resistance is increasingly apparent. Currently, the gram-negative bacteria
Beggs, Grace Anne
core   +1 more source

MTRR gene variants may predispose to the risk of Congenital Heart Disease in Down syndrome patients of Indian origin

open access: yesEgyptian Journal of Medical Human Genetics, 2017
Background: Down syndrome (DS), also called as trisomy 21, is one of the most leading cause of intellectual disability. DS is associated with a number of phenotypes including Congenital Heart Disease (CHD), Leukemia, Alzheimer’s disease, Hirschsprung’s ...
Ambreen Asim   +2 more
doaj   +1 more source

Neisseria gonorrhoeae Isolates with Reduced Susceptibility to Cefixime and Ceftriaxone: Association with Genetic Polymorphisms in penA, mtrR, porB1b, and ponA [PDF]

open access: yes, 2007
The recent emergence and transmission of Neisseria gonorrhoeae isolates with reduced susceptibility to expanded-spectrum cephalosporins such as cefixime and ceftriaxone have been reported.
Unemo, M.   +3 more
core   +1 more source

LABORATORY AND GENETIC PREDICTION OF THE RISK OF ATRIAL FIBRILLATION IN PATIENTS WITH CORONARY HEART DISEASE

open access: yesКубанский научный медицинский вестник, 2017
The paper studied the frequency of polymorphisms of hemostasis in patients with coronary heart disease, living in the Krasnodar region. Of the 13 patients with atrial fibrillation documented confirmed, 11 patients revealed mutations of genes of the ...
D. I. PANCHENKO, A. S. ADAMCHIK
doaj   +1 more source

Relative gene expression levels of MTHFR and MTRR in in vitro PBMCs.

open access: yes, 2013
Relative mRNA levels of MTHFR (a) and MTRR (b) after 24 h treatment with cocoa extract (25 mg/L or 50 mg/L) or with vehicle alone. Results represent mean±SEM expression levels normalized to RPLP0.
Neus Anglés (180855)   +7 more
core   +1 more source

Analysis of MTR and MTRR Gene Polymorphisms in Chinese Patients With Ventricular Septal Defect

open access: yesApplied Immunohistochemistry & Molecular Morphology, 2018
Background: Congenital heart defects (CHDs) are the most common birth defects and ventricular septal defects (VSDs) are one of the most common types of CHDs. Genes involved in homocysteine/folate metabolism may play important roles in CHDs.
Su, Jiang, Li, Zhongzhi
openaire   +3 more sources

Association between cobalamin and folate deficiency and the presence of the MTR A2756G and MTRR A66G polymorphisms in pregnant women and their newborns

open access: yes, 2018
A metionina sintase redutase (MTRR) catalisa a redução da cobalamina (Cbl) oxidada a metilcobalamina. Em presença de folato, a metionina sintase (MTR) utiliza a metilcobalamina como cofator na metilação da homocisteína (tHcy) a metionina.
Favaro, Patricia Barbosa
core   +1 more source

Overexpression of the MtrC-MtrD-MtrE Efflux Pump Due to an mtrR Mutation Is Required for Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae [PDF]

open access: yes, 2002
The importance of the mtrCDE-encoded efflux pump in conferring chromosomally mediated penicillin resistance on certain strains of Neisseria gonorrhoeae was determined by using genetic derivatives of penicillin-sensitive strain FA19 bearing defined ...
W. L. Veal   +5 more
core   +1 more source

MTHFR and MTRR polymorphisms associations with unexplained female infertility

open access: yesInternational Journal of Medicine and Medical Research
Polymorphic alleles in genes of folate metabolism are associated with such failures of female infertility like impaired ovulation or fertilisation; however, the data about the single gene polymorphisms in genes which code the enzymes of folate metabolism are controversial.
openaire   +1 more source

Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon [PDF]

open access: yes, 2017
The MtrCDE efflux pump of Neisseria gonorrhoeae contributes to gonococcal resistance to a number of antibiotics used previously or currently in treatment of gonorrhea, as well as to host-derived antimicrobials that participate in innate defense ...
Rouquette-Loughlin, Corinne E.   +9 more
core   +1 more source

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