Results 161 to 170 of about 4,722 (199)

Recent Updates on the Role of Genetic and Epigenetic Factors in the Pathogenesis of the Metabolic Syndrome. [PDF]

open access: yesDiabetes Metab Syndr Obes
Ariyanto EF   +15 more
europepmc   +1 more source

H 2 dependent modulation of Mtr activity by small protein MtrR in Methanosarcina mazei

open access: yes
Habenicht T   +6 more
europepmc   +1 more source

The Roles of MTRR and MTHFR Gene Polymorphisms in Colorectal Cancer Survival [PDF]

open access: yesNutrients, 2022
Background: Paradoxically epidemiological data illustrate a negative relationship between dietary folate intake and colorectal cancer (CRC) risk. The occurrence and progression of CRC may be influenced by variants in some key enzyme coding genes in the folate metabolic pathway.
John R McLaughlin   +2 more
exaly   +4 more sources

Analysis of MTHFR and MTRR Gene Polymorphisms in Iranian Ventricular Septal Defect Subjects [PDF]

open access: yesInternational Journal of Molecular Sciences, 2013
Ventricular septal defect (VSD) is one of the most common types of congenital heart defects (CHD). There are vivid multifactorial causes for VSD in which both genetic and environmental risk factors are consequential in the development of CHD. Methionine synthase reductase (MTRR) and methylenetetrahydrofolate reductase (MTHFR) are two of the key ...
Fauziah Othman   +2 more
exaly   +4 more sources

Associations of MTHFR C677T and MTRR A66G Gene Polymorphisms With Metabolic Syndrome: A Case-Control Study in Northern China

open access: yesInternational Journal of Molecular Sciences, 2014
Prior evidence indicates that homocysteine plays a role in the development of metabolic syndrome (MetS). Methylenetetrahydrofolate reductase (MTHFR) C677T and methionine synthase reductase (MTRR) A66G polymorphisms are common genetic determinants of ...
Guifan Sun, Shujun Fan, Xueyuan Zhi
exaly   +2 more sources

Structural, Biochemical, and in Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae.

open access: yesJournal of Bacteriology, 2019
Neisseria gonorrhoeae responds to host-derived antimicrobials by inducing the expression of the mtrCDE-encoded multidrug efflux pump, which expels microbicides, such as bile salts, fatty acids, and multiple extrinsically administered drugs, from the cell.
Richard G Brennan   +2 more
exaly   +2 more sources

MTRR and MTHFR Polymorphism: Link to Down Syndrome?

American Journal of Medical Genetics, Part A, 2002
Anne Parle-McDermott   +2 more
exaly   +2 more sources

Riboflavin Status Modifies the Effects of Methylenetetrahydrofolate Reductase (MTHFR) and Methionine Synthase Reductase (MTRR) Polymorphisms on Homocysteine

open access: yesGenes and Nutrition, 2014
Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase red uctase (MTRR), riboflavin- dependent enzymes, participat e in homocysteine metabolism. Reported effects of riboflavin status on the association between the MTHFR 677C [
Joan D Fernandez-Ballart   +2 more
exaly   +3 more sources

Associations of MTRR A66G Polymorphism and Promoter Methylation With Ischemic Stroke in Patients With Hyperhomocysteinemia

Journal of Gene Medicine, 2020
Abstract Background Patients with hyperhomocysteinemia (HHcy) have a higher risk of developing ischemic stroke (IS). The association between MTRR A66G polymorphism and promoter methylation with IS in patients with HHcy is also uncertain.
Qinglin Zhao   +2 more
exaly   +3 more sources

???????????? ???????????????????????????????? ?????????????????????????? ?????????? MTHFR ?? MTRR ?? ?????????????? ??????????????????

2021
Aim. Analysis of single nucleotide polymorphisms C677T, A1298C and A66G of MTHFR and MTRR one-carbon metabolism genes in patients with various forms of psoriasis in Ukrainian population. Methods. A molecular genetic analysis of 77 patients with vulgaris and arthropathic psoriasis by PCR-RFLP was carried out. Results.
openaire   +2 more sources

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