Results 181 to 190 of about 9,945 (212)

Mapping Allergen B‐ and T‐Cell Epitopes: Technological Advances and Their Role in Precision Allergy Therapy

Allergy, EarlyView.
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche, Josefine Corneliussen, Kristoffer H. Johansen, Alexandre Ruiz‐Carrasco, Caroline Paulsen, Yuchen Li, Carolina Barra, Sandhya Bangaru, Monica L. Fernández‐Quintero, Ewa Bartko, Lars Blom, Esperanza Rivera‐de‐Torre   +11 more
wiley   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Mucosal-Associated Invariant T Cells in Health and Disease. [PDF]

MedComm (2020)
Zhao Y, Ou FM, Liang D, Gao Y, Li QQ, Kuang YQ.   +5 more
europepmc   +1 more source

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

Clinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole, Ingrid Laing, Ryan Mead‐Hunter, Peter Le Souef, Guicheng Zhang   +4 more
wiley   +1 more source

Mucosal-Associated Invariant T Cells Drive Bile Duct Inflammation. [PDF]

Cell Mol Gastroenterol Hepatol
Nordhus KS, Zheng F, Berntsen NL, Ramberg OH, Valestrand L, Øgaard J, Chung BK, Jiang X, Melum E.   +8 more
europepmc   +1 more source

Cleaning Efficacy and Surface Alterations of Titanium and Zirconia Implant Abutments Following Mechanical Instrumentation: An In Vitro Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate the cleaning efficacy, quantitative and qualitative surface modifications of titanium (Ti) and zirconia (Zr) abutments following instrumentation with twelve mechanical instrumentation modalities. Materials and Methods Twenty‐four Ti and twenty‐four Zr abutments were divided by marginal grooves into 36 test and 12 control
Marina Salah Kamel, Axel Spahr, Tim Badgery‐Parker, Tihana Divnić‐Resnik   +3 more
wiley   +1 more source

"From inflammation to fibrosis: a proposed role of mucosal-associated invariant T cells in lichen sclerosus - a conceptual framework". [PDF]

Front Immunol
Kasprowicz-Furmańczyk M, Owczarczyk-Saczonek A.   +1 more
europepmc   +1 more source

Single‐Cell and Spatial Analysis Reveal the Differences Between Left‐Sided and Right‐Sided Colorectal Cancer

Cell Proliferation, EarlyView.
Single‐cell and spatial analysis revealed distinct CRC microenvironments by tumour laterality. Right‐sided tumours showed enhanced germinal centre B cells, CXCL13+ T cells, and organized TLS‐immune crosstalk via CCL19/21‐CCR7, suggesting better immunotherapy response.
Zongnai Zhang, Jiaqi Xu, Yingchao Wu, Tao Liu, Junling Zhang, Mai Zhou, Jie Qiao, Heng Pan, Xin Wang   +8 more
wiley   +1 more source

Unconventional guardians of the brain: MAIT cells as emerging players in glioblastoma immunity. [PDF]

Front Immunol
Eddy EM, Patton T, Barrow AD, Corbett AJ.   +3 more
europepmc   +1 more source

Mucosal-associated invariant T cells respond to colonic microbiome alterations during acute HIV infection. [PDF]

Mucosal Immunol
Vimonpatranon S, Mika SK, Pang APS, Machmach K, Lima NS, Godbole S, Sajjaweerawan C, Longtine ER, Henry AR, Laboune F, Metz E, Ratnaratorn N, Phuang-Ngern Y, Sacdalan C, Ake JA, Shacklett BL, Sandberg JK, Rerknimitr R, Phanuphak N, Vasan S, Douek DC, Corley MJ, Schuetz A, Paquin-Proulx D.   +23 more
europepmc   +1 more source