Results 21 to 30 of about 608,623 (303)

High-Resolution Quantitative Mapping of Macaque Cervicovaginal Epithelial Thickness: Implications for Mucosal Vaccine Delivery

Frontiers in Immunology, 2021
Vaginal mucosal surfaces naturally offer some protection against sexually transmitted infections (STIs) including Human Immunodeficiency Virus-1, however topical preventative medications or vaccine designed to boost local immune responses can further ...
Kathleen L. Vincent, Patrice A. Frost, Patrice A. Frost, Massoud Motamedi, Edward J. Dick, Edward J. Dick, Jingna Wei, Jinping Yang, Robert White, Marie-Claire Gauduin, Marie-Claire Gauduin   +10 more
doaj   +1 more source

Live mucosal vaccination stimulates potent protection via varied CD4+ and CD8+ T cell subsets against wild-type Brucella melitensis 16M challenge

Frontiers in Immunology, 2022
Re-emerging zoonotic pathogen Brucella spp. continues to impact developing countries and persists in expanding populations of wildlife species in the US, constantly threatening infection of our domestic herds. The development of improved animal and human
Zakia I. Goodwin, Xinghong Yang, Carol Hoffman, David W. Pascual   +3 more
doaj   +1 more source

TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP [PDF]

, 2015
TRPM8 is the molecular sensor for cold; however, the physiological role of TRPM8+ neurons at mucosal surfaces is unclear. Here we evaluated the distribution and peptidergic properties of TRPM8+ fibers in naive and inflamed colons, as well as their role ...
Lee, J, Herdman, DS, Harris, Alexandra R, Herdman, D. S., Harris, AR, Blackshaw, L Ashley, Raz, Eyal, Lee, J., Blackshaw, L. A., Gareau, Melanie G, Raz, E., Lee, Jihyung, Raz, E, Corr, Maripat, Gareau, MG, Peiris, M, de Jong, Petrus R, Gareau, M. G., Herdman, David S, De Jong, P. R., Paniagua, A, Blackshaw, LA, Corr, M, Takahashi, Naoko, de Jong, PR, Bertin, S., Paniagua, A., Bertin, Samuel, Takahashi, N, Takahashi, Naoki, Peiris, M., Peiris, Madusha, Paniagua, Alan, Bertin, S, Harris, A. R., MS CGO   +35 more
core   +1 more source

Salivary Antibody Responses to Two COVID-19 Vaccines following Different Vaccination Regimens

Vaccines, 2023
Background: To date, little is known about the salivary mucosal immune response following different COVID-19 vaccine types or after a booster (3rd) dose of the BNT162b2 (BNT) vaccine.
Hassan Alkharaan, Hatem Al-Qarni, Muath A. Aldosari, Mohammed Alsaloum, Ghada Aldakheel, Mohammed W. Alenazi, Naif Khalaf Alharbi   +6 more
doaj   +1 more source

HIV pathogenesis in the female genital tract during chronic HIV infection : the impact of inflammation, T cell memory differentiation status and homeostatic cytokines on mucosal T cell immunity [PDF]

, 2010
Includes bibliographical references (leaves 124-150).The female genital tract serves as the major portal of entry for human immunodeficiency virus (HIV).
Gumbi, Pamela
core   +1 more source

Mucosal Melanoma of Eustachian Tube: A Case Report

, 2022
Mucosal melanoma originating from the eustachian tube is very rare, and only 15 cases were reported so far. In this study, we report a case of mucosal melanoma from the eustachian tube which was surgically managed, followed by chemoradiotherapy.
Sang Duk Hong, Bum Kim, Min, Min Bum Kim, Cho, Yang-Sun, Duk Hong, Sang, Yung Jee Kang, Yang-Sun Cho, Jee Kang, Yung   +7 more
core   +1 more source

Ontogeny of Mucosal Immunity and Aging

, 2015
The mucosal immune system begins development in utero at as early as 40 days gestation, and by the time of birth all components of the system are in place and have the potential to effectively respond to antigenic challenge.
Maree Gleeson, Gleeson, M, Allan W. Cripps, Cripps, AW   +3 more
core   +1 more source

Middle Ear and Eustachian Tube Mucosal Immunology

, 2015
Mucosal immune responses within the middle ear and eustachian tube generally provide an effective and efficient response to the presence of microbial pathogens, with approximately 80% of clinically recognizable middle ear infections resolved within 7 ...
Lim, DJ, Yuichi Kurono, Massa, HM, Kurono, Y, Helen M. Massa, Allan W. Cripps, Cripps, AW, David J. Lim   +7 more
core   +1 more source

Mucosal Immunology and Models of Mucosal HIV Infection [PDF]

, 1996
The mucosa associated lymphoid tissue regulates and coordinates immune responses against mucosal pathogens. Mucosal tissues are the major targets exposed to HIV during transmission. In this paper we describe in vitro models of HIV mucosal infection using
M. B. Ortigão-de-Sampaio, G. E. Griffin, R. Shattock, L. R. R. Castello-Branco   +3 more
core   +3 more sources

Inter-laboratory harmonization of microsphere immunoassays for SARS-CoV-2 antibody detection in contrived dried blood spots and oral fluids

Microbiology Spectrum
Dried blood spots (DBS) and oral fluids (OF) are easily attainable biospecimen types that enabled population-scale antibody monitoring for SARS-CoV-2 exposure and vaccination.
Kate L. DeRosa, Nora Pisanic, Kate Kruczynski, Christopher D. Heaney, Linda M. Styer, Nicholas J. Mantis   +5 more
doaj   +1 more source