Results 1 to 10 of about 202,905 (306)
Restoring mucosal barrier homeostasis by in situ formation of a living-synthetic therapeutic coating [PDF]
Nature CommunicationsThe mucosal barrier consisting of physicochemical, immune, and microbial components is the first line of defense against external stimuli. Breakdown of the mucosal barrier causes the occurrences of various diseases, while methods capable of ...
Wei Yu +9 more
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Comparison of the transmembrane mucins MUC1 and MUC16 in epithelial barrier function. [PDF]
PLoS ONE, 2014 Membrane-anchored mucins are present in the apical surface glycocalyx of mucosal epithelial cells, each mucosal epithelium having at least two of the mucins.
Ilene K Gipson +3 more
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Editorial: Allergen source-specific mucosal barrier disruptors [PDF]
Frontiers in AllergyRajna Minić +3 more
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Regulatory Role of IGF2BP2 in Intestinal Mucosal Barrier Dysfunction in Ulcerative Colitis [PDF]
The Turkish Journal of GastroenterologyBackground/Aims: Ulcerative colitis (UC), an idiopathic and chronic inflammatory disease, primarily targets the mucosal lining of the colon. This research endeavors to reveal the mechanism of insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2 ...
Ruifan Li, Bin Gu, Anli Lv
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Journal of Advanced Research, 2023 Background: Previous studies have focused on the involvement of small nucleolar RNAs (snoRNAs) and SNHGs in tumor cell proliferation, apoptosis, invasion, and metastasis via multiple pathways, including phosphatidylinositol-3-kinase/protein kinase B ...
Tian Yang, Jun Shen
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Tight junction channel regulation by interclaudin interference
Nature Communications, 2022 Tight junctions are formed by claudin proteins that can be classified as pore- or barrier-forming. Here, Shashikanth et al. report a third function, termed interclaudin interference, in which one claudin inhibits pore function of another claudin by ...
Nitesh Shashikanth +7 more
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Quantitative dose-response analysis untangles host bottlenecks to enteric infection
Nature Communications, 2023 Here, using Citrobacter rodentium colonization of mice as a model, the authors characterize the impact of pathogen dose on the number of bacteria that initiate infection in the mouse gut, providing a framework for quantifying the host bottlenecks that ...
Ian W. Campbell +3 more
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The Journal of Poultry Science, 2022 The mucosa of the intestine and oviduct of hens are susceptible to pathogens. Pathogenic infections in the mucosal tissues of laying hens lead to worsened health of the host animal, decreased egg production, and bacterial contamination of eggs ...
Takahiro Nii
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Chloride channels regulate differentiation and barrier functions of the mammalian airway. [PDF]
, 2020 The conducting airway forms a protective mucosal barrier and is the primary target of airway disorders. The molecular events required for the formation and function of the airway mucosal barrier, as well as the mechanisms by which barrier dysfunction ...
Caplan, Michael J +14 more
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Tight Junctions as Targets and Effectors of Mucosal Immune HomeostasisSummary
Cellular and Molecular Gastroenterology and Hepatology, 2020 Defective epithelial barrier function is present in maladies including epidermal burn injury, environmental lung damage, renal tubular disease, and a range of immune-mediated and infectious intestinal disorders. When the epithelial surface is intact, the
Li Zuo, Wei-Ting Kuo, Jerrold R. Turner
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