Results 11 to 20 of about 202,905 (306)

PEGylated bacteria restore intestinal mucosal barrier [PDF]

Acta Pharmaceutica Sinica B
Menghang Zu, Xue Xia, Bo Xiao
doaj   +4 more sources

Editorial: The mucosal barrier to infection

Frontiers in Cellular and Infection Microbiology, 2023
Yong Hua Sheng, Li Zhang
doaj   +3 more sources

Disulfiram alleviates acute lung injury and related intestinal mucosal barrier impairment by targeting GSDMD-dependent pyroptosis

Journal of Inflammation, 2022
Background Pyroptosis was implicated in acute lung injury (ALI). Disulfiram is reported as an effective pyroptosis inhibitor by inhibiting gasdermin D(GSDMD).
Jiping Zhao, Hong Wang, Jintao zhang, Fuwei Ou, Junfei Wang, Tian Liu, Jinxiang Wu   +6 more
doaj   +1 more source

The Role of Intestinal Mucosal Barrier in Autoimmune Disease: A Potential Target

Frontiers in Immunology, 2022
Autoimmune diseases are a series of diseases involving multiple tissues and organs, characterized by the over production of abnormal multiple antibodies.
Jia An, Yuqing Liu, Yiqi Wang, Ru Fan, Xiaorong Hu, Fen Zhang, Jinhua Yang, Junwei Chen   +7 more
doaj   +1 more source

Innate mechanism of mucosal barrier erosion in the pathogenesis of acquired colitis

iScience, 2023
Summary: The colonic mucosal barrier protects against infection, inflammation, and tissue ulceration. Composed primarily of Mucin-2, proteolytic erosion of this barrier is an invariant feature of colitis; however, the molecular mechanisms are not well ...
Won Ho Yang, Peter V. Aziz, Douglas M. Heithoff, Yeolhoe Kim, Jeong Yeon Ko, Jin Won Cho, Michael J. Mahan, Markus Sperandio, Jamey D. Marth   +8 more
doaj   +1 more source

Intestinal Barrier, Permeability and Nonspecific Inflammation in Functional Gastrointestinal Disorders

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2020
Aim of review. Description of intestinal mucosal barrier permeability disruption causes as morbid factors in gastrointestinal tract (GIT) functional disorders.General provisions.
A. L. Kovaleva, E. A. Poluektova, O. S. Shifrin   +2 more
doaj   +1 more source

Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes

Frontiers in Immunology, 2021
Mucosal surfaces, as a first barrier with the environment are especially susceptible to damage from both pathogens and physical trauma. Thus, these sites require tightly regulated repair programs to maintain barrier function in the face of such insults ...
Joshua R. Cox, Joshua R. Cox, Sheena M. Cruickshank, Amy E. Saunders, Amy E. Saunders   +4 more
doaj   +1 more source

Biliary Mucosal Barrier and Microbiome [PDF]

Visceral Medicine, 2015
<b><i>Background:</i></b> The biliary system is in continuous contact with the complex microbiota of the intestine. Microbial products have recently been proposed as potential triggers for biliary diseases. <b><i>Methods:</i></b> The aim of this review is to provide a summary of the current knowledge ...
Julien Verdier, Tom Luedde, Gernot Sellge   +2 more
openaire   +2 more sources

Perspectives on Mucosal Vaccines: Is Mucosal Tolerance a Barrier? [PDF]

The Journal of Immunology, 2007
AbstractMucosal administration of Ags induces specific Abs in external secretions and systemic unresponsiveness termed oral or mucosal tolerance. The dominant response depends on the species studied, the nature, dose, frequency, route of Ag application, and the use of adjuvants. The temporal sequence of Ag exposure determines the quality of the ensuing
Jiri, Mestecky, Michael W, Russell, Charles O, Elson   +2 more
openaire   +2 more sources

Is intra-abdominal hypertension a missing factor that drives multiple organ dysfunction syndrome? [PDF]

, 2014
In a recent issue of Critical Care, Cheng and colleagues conducted a rabbit model study that demonstrated that intra-abdominal hypertension (IAH) may damage both gut anatomy and function. With only 6 hours of IAH at 25 mmHg, these authors observed an 80%
De Waele, Jan, Kirkpatrick, Andrew W, Laupland, Kevin, Roberts, Derek J   +3 more
core   +2 more sources