Results 111 to 120 of about 305,145 (241)

Retrospective Analysis of Familial Clustering for Malignant Melanoma

, 2003
Background: Malignant Melanoma (MM) is familial in 5-7% of cases. Germline mutations of the CDKN2 and CDK4 genes are involved in the pathogenesis of hereditary MM, but the high frequency of familial clustering suggests other genes involved.
DELFINO, MARIO, PENSABENE, MATILDE, SPAGNOLETTI, ILARIA, SCALVENZI, MASSIMILIANO, MOLEA, GUIDO, CAPUANO, IDA, PEPE, STEFANO, CONTEGIACOMO, ALMA, FABBROCINI, GABRIELLA   +8 more
core  

Biomarkers Predictive of Immunotherapy Efficacy in Head and Neck Squamous Cell Carcinoma: Current Insights and Future Perspectives

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT With the approval of immunotherapies by regulatory bodies, head and neck squamous cell carcinoma (HNSCC) treatment has been revolutionized, and anti‐programmed cell death‐1 (anti‐PD‐1) agents are now the standard for platinum‐resistant recurrent/metastatic HNSCC.
Xiao‐Tong Yan, Zhao‐Hong An, Chang‐Ming An   +2 more
wiley   +1 more source

Endoscopic Surgery for Sinonasal Mucosal Melanoma

, 2013
Objective: To review our clinical experience in the management of sinonasal mucosal melanoma using minimally invasive surgical techniques. Design: Retrospective chart review of patients undergoing endoscopic resection of sinonasal mucosal melanoma ...
Rivera, Andrew M, Casiano, Roy R, Lieberman, Seth M   +2 more
core   +1 more source

AI‐Powered TAT‐Net Hyperspectral Imaging for Rapid and Accurate Differentiation of Sinonasal Inverted Papilloma and Malignancy

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Sinonasal inverted papilloma (IP) and malignancies share overlapping clinical and endoscopic features, and conventional histopathology frequently requires time‐consuming adjunct immunohistochemistry. Hyperspectral imaging (HSI) can capture subtle spectral changes associated with malignant transformation that are not apparent on ...
Hao‐Miao Zhao, Jia‐Chang Kong, Yun‐Ze Li, Wei Li, Xin Feng   +4 more
wiley   +1 more source

Large‐Scale Applications of Plasma Technologies: Progresses and Challenges

High Voltage, EarlyView.
ABSTRACT Plasma technologies convert electrical power into energetic electrons, ions, reactive species, radiation and heat, thereby breaking through the bottleneck of purely thermal or chemical routes and bringing impressive changes to our world. This roadmap reviews the progress and challenges of plasma technologies from a large‐scale and application ...
Pankaj Attri, Liuyang Bai, Dmitry Batomunkuev, Xueke Che, Guoxing Chen, Zhitong Chen, Wei Cui, Liguang Dou, Zhi Fang, Yangyang Fu, Fausto Gallucci, Yiming Guo, Bangdou Huang, Yinghong Li, Sirui Li, Hua Liang, Liangliang Lin, Dingxin Liu, Xiangyang Liu, Xinpei Lu, Ruonan Ma, Lanlan Nie, Guanghui Niu, Yuge Ouyang, Tao Shao, Jing Sun, Yong Tang, Xin Tu, Sergey P. Vashchenko, Hang Wang, Xianjie Wang, Anke Weidenkaff, Yun Wu, Haohan Xie, Shaojun Xu, Zongxian Yang, Fangli Yuan, Cheng Zhang, Hao Zhang, Jishen Zhang, Shuai Zhang, Yejian Zhang, Zhe Zhang, Zhibo Zhang, Peng Zhao, Shicheng Zhao, Linlin Zhong, Renwu Zhou, Zhenhua Zhou, Xi Zhu, Yifei Zhu, Haohua Zong   +51 more
wiley   +1 more source

Malignant Melanoma of Nose and Paranasal Sinuses: 2 Case Reports [PDF]

, 2010
Malignant melanoma is one of the rare and highly aggressive diseases of the sinonasal cavity. High index of suspicion is required for diagnosis as the patient usually presents with non specific signs and symptoms.
Gupta, N, Sanjeev Bhagat, Varshney, S, Singh, R, Saurabh Varshney, Rakesh Singh, Bhagat, S, Bist, SS, Sampan Singh Bist, Nitin Gupta   +9 more
core  

Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms

The Journal of Dermatology, EarlyView.
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du, Anika Jallorina, Toru Yoshino, Lingyu Bao, Han Bao, Victor Chang, Henry K. Wong, Derek V. Chan, Stephen K. Richardson, Mary F. Lee‐Wong   +9 more
wiley   +1 more source

Mucosal Melanoma Arising in the Eustachian Tube : A Case Report [PDF]

, 2004
Mucosal melanoma is a very rare disease. Most cases of mucosal melanoma have their origins in the head and neck region. To date, only three cases of melanoma originating from the eustachian tube have been reported.
이원상, 한수진
core  

Mucosal malignant melanoma - a clinical, oncological, pathological and genetic survey

, 2016
Mucosal melanomas constitute 1.3% of all melanomas and they may develop in any mucosal membrane. Conjunctival melanomas (0.5/million/year) and melanomas in the sinonasal cavity (0.5/million/year) are the most common, followed by anorectal melanomas (0.4 ...
Heegaard, Steffen, Mikkelsen, Lauge H, Prause, Jan U, Larsen, Ann-Cathrine, von Buchwald, Christian, Drzewiecki, Krzysztof T   +5 more
core   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source