Results 121 to 130 of about 305,145 (241)

Primary mucosal melanoma: A case report

open access: yesJournal of Craniomaxillofacial Research, 2017
Malignant melanoma is an aggressive malignancy of melanocytes affecting both skin and mucosa. Primary oral melanoma occurs 0.2-8% of all melanomas and accounts for 0.5% of all oral malignancies.
Fereshteh Baghai   +4 more
doaj  

A Curious Case of Primary Gastric Mucosal Melanoma

open access: yesThe Korean Journal of Gastroenterology
Malignant melanoma is a neoplasm of melanin-producing cells predominantly of cutaneous origin, which uncommonly develops within gut mucosa. We present the case of a 58-year-old woman with complaints of abdominal pain, loss of appetite and weight ...
Zahabia Sohail   +3 more
doaj   +1 more source

Guideline on the Management of Melanoma

open access: yes, 2016
Objective.1. The Guideline for the Management of Melanoma has been developed in an attempt to improve  management through the process of locating the best available evidence on which to base decisions.
Board, Melanoma Advisory
core  

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

open access: yesAllergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz   +22 more
wiley   +1 more source

Trained Immunity in Childhood Vaccination

open access: yesActa Paediatrica, EarlyView.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai   +2 more
wiley   +1 more source

Melanoma In Situ of the Hard Palate

open access: yesEar, Nose & Throat Journal
Mucosal melanoma of the oral cavity is rare and highly aggressive, thought to represent less than 1% of melanomas. Within this subgroup, melanoma in situ has been rarely described.
Teresa G. Vos MD   +2 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

open access: yesCancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren   +11 more
wiley   +1 more source

A case series on oral mucosal melanoma: Presenting beyond the typical

open access: yesIndian Journal of Dental Research
Objectives: To present atypical clinical and demographic presentations of oral mucosal melanoma and highlight diagnostic and therapeutic challenges. Methods: Two clinically unusual cases of oral mucosal melanoma were evaluated with clinical examination ...
Astha Kapoor, Sunita Gupta, Sujoy Ghosh
doaj   +1 more source

Single‐Cell and Spatial Analysis Reveal the Differences Between Left‐Sided and Right‐Sided Colorectal Cancer

open access: yesCell Proliferation, EarlyView.
Single‐cell and spatial analysis revealed distinct CRC microenvironments by tumour laterality. Right‐sided tumours showed enhanced germinal centre B cells, CXCL13+ T cells, and organized TLS‐immune crosstalk via CCL19/21‐CCR7, suggesting better immunotherapy response.
Zongnai Zhang   +8 more
wiley   +1 more source

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