Results 151 to 160 of about 109,419 (254)

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

open access: yesMed Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng   +14 more
wiley   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal   +9 more
wiley   +1 more source

Clinic‐Based Transnasal Marsupialization for the Treatment of Congenital Dacryocystocele

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the feasibility and outcomes of endoscopic intranasal marsupialization as treatment for congenital dacryocystocele, performed under topical anesthesia in a clinical setting. Study Design A retrospective review was conducted at a tertiary pediatric care hospital spanning from 2014 to 2024.
Camille Caron   +4 more
wiley   +1 more source

Glucocorticoids Impair the Airway Epithelial Barrier via Autophagy‐Associated Apoptosis in Asthma: A Preliminary Study Both In Vitro and In Vivo

open access: yesPediatric Discovery, EarlyView.
Mechanism underlying the negative effects of glucocorticoids on the airway epithelial barrier. Glucocorticoids upregulate autophagy factors and downregulate anti‐autophagy factors. Enhanced autophagy promotes excessive apoptosis and epithelial detachment, impairing airway barrier function.
Hao You   +10 more
wiley   +1 more source

Early Growth Response 1‐Associated Epithelial Autophagy‐Related Changes in Allergic Airway Inflammation

open access: yesPediatric Discovery, EarlyView.
House dust mite (HDM) exposure induces early growth response 1 (EGR1) expression in airway epithelial cells and is accompanied by autophagy‐associated alterations, including increased LC3B‐II and Vps34 levels and decreased p62 abundance. Manipulation of EGR1 expression modulates these autophagy‐related changes, whereas pharmacological inhibition of ...
Xinyang Wang   +3 more
wiley   +1 more source

Nasal mucus secretion.

open access: yesEar, nose, & throat journal, 1984
Z, Marom, J, Shelhamer, M, Kaliner
openaire   +1 more source

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