Results 61 to 70 of about 1,562 (148)

ATP-Induced Shrinkage of DNA with MukB Protein and the MukBEF Complex of Escherichia coli [PDF]

open access: yesJournal of Bacteriology, 2008
ABSTRACT Fluorescence microscopic observation of individual T4 DNA molecules revealed that the MukBEF complex (bacterial condensin) and its subunit, the MukB (a member of the SMC [structural maintenance of chromosomes] superfamily) homodimer, of Escherichia coli markedly shrunk large DNA molecules in the ...
Ning, Chen   +7 more
openaire   +2 more sources

SMC-mediated chromosome mechanics: a conserved scheme from bacteria to vertebrates? [PDF]

open access: yes, 1999
The assembly of mitotic chromosomes is a fundamental cellular event that ensures the faithful segregation of genetic information during cell division. It involves two processes that are, in principle, mechanistically distinct.
Hirano, T.
core   +1 more source

Group II Intron Protein Localization and Insertion Sites Are Affected by Polyphosphate [PDF]

open access: yes, 2008
Mobile group II introns consist of a catalytic intron RNA and an intron-encoded protein with reverse transcriptase activity, which act together in a ribonucleoprotein particle to promote DNA integration during intron mobility.
Lambowitz, Alan M.   +5 more
core   +5 more sources

3D visualization software to analyze topological outcomes of topoisomerase reactions. [PDF]

open access: yes, 2008
The action of various DNA topoisomerases frequently results in characteristic changes in DNA topology. Important information for understanding mechanistic details of action of these topoisomerases can be provided by investigating the knot types resulting
Darcy, I.K., Scharein, R.G., Stasiak, A.
core   +2 more sources

Determining cellular CTCF and cohesin abundances to constrain 3D genome models. [PDF]

open access: yes, 2019
Achieving a quantitative and predictive understanding of 3D genome architecture remains a major challenge, as it requires quantitative measurements of the key proteins involved.
Cattoglio, Claudia   +11 more
core   +2 more sources

Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli [PDF]

open access: yes, 2011
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Arsuaga, Javier   +5 more
core   +2 more sources

Identification and characterization of the smbA gene, a suppressor of the mukB null mutant of Escherichia coli [PDF]

open access: yesJournal of Bacteriology, 1992
The mukB gene encodes a protein involved in chromosome partitioning in Escherichia coli. To study the function of this protein, we isolated from the temperature-sensitive mukB null mutant and characterized 56 suppressor mutants which could grow at 42 degrees C. Ten of the mutants also showed cold-sensitive growth at 22 degrees C.
K, Yamanaka   +3 more
openaire   +2 more sources

Cohesin biology meets the loop extrusion model [PDF]

open access: yes, 2017
Extensive research has revealed that cohesin acts as a topological device, trapping chromosomal DNA within a large tripartite ring. In so doing, cohesin contributes to the formation of compact and organized genomes.
Barrington, C, Finn, R, Hadjur, S
core   +1 more source

Distribution of the Escherichia coli structural maintenance of chromosomes (SMC)‐like protein MukB in the cell [PDF]

open access: yesMolecular Microbiology, 2001
Fluorescent polyclonal antibodies specific for MukB have been used to study its localization in Escherichia coli. In wild‐type cells, the MukB protein appeared as a limited number of oblong shapes embracing the nucleoid. MukB remained associated with the nucleoid in the absence of DNA replication.
den Blaauwen, T.   +3 more
openaire   +4 more sources

Physical and functional interaction between the condensin MukB and the decatenase topoisomerase IV in Escherichia coli [PDF]

open access: yesProceedings of the National Academy of Sciences, 2010
Proper geometric and topological organization of DNA is essential for all chromosomal processes. Two classes of proteins play major roles in organizing chromosomes: condensin complexes and type II topoisomerases. In Escherichia coli , MukB, a structural maintenance of chromosome-like component of the bacterial ...
Ryo, Hayama, Kenneth J, Marians
openaire   +2 more sources

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