Results 71 to 80 of about 21,910,954 (295)

Multi-agent Reactive Systems [PDF]

, 2002
We present a formalism for programming complex multiagent reactive systems in a structured manner. The motivation behind this work is to obtain a simple semantic framework for such reactive systems. The approach followed is to build upon a timed extension of concurrent constraint programs that have been used to present an elegant declarative framework ...
openaire   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

DESIRE: Modelling Multi-Agent Systems in a Compositional Formal Framework [PDF]

, 1997
This paper discusses an example of the application of a high-level modelling framework which enables both the specification and implementation of a system's conceptual design.
Jennings, N. R., Dunin-Keplicz, B. M., Treur, J., Brazier, F. M. T.   +3 more
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Trust in multi-agent systems [PDF]

The Knowledge Engineering Review, 2004
Trust is a fundamental concern in large-scale open distributed systems. It lies at the core of all interactions between the entities that have to operate in such uncertain and constantly changing environments. Given this complexity, these components, and the ensuing system, are increasingly being conceptualised, designed, and built using agent-based ...
Sarvapali D. Ramchurn, Trung Dong Huynh, Nicholas R. Jennings   +2 more
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Sistem Load Balancing Menggunakan Least Time First Byte dan Multi Agent System

Jurnal Nasional Teknik Elektro dan Teknologi Informasi, 2017
Network activity has increased in every year due to rapid growth of internet users. This phenomenon eventually increases the load server. The high load on server makes server down.
Muhammad Faizal Afriansyah, Maman Somantri, Munawar Agus Riyadi   +2 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

An Adaptive Normative Multi Agent System using Web 3.0 for e-Learning Platform

Online Academic Journal of Information Technology, 2013
The growing concern for education and innovative technologies has led to a new dimension of learning. The paper proposes a new framework NormATel using the concept of Normative Multi-Agent system, Activity Theory and e-Learning.
.ımran Ali Siddiqu, Neelu Jyoti Ahuja, Manuj Darbari, Namrata Dhanda   +3 more
doaj   +1 more source

Formalisms for multi-agent systems [PDF]

The Knowledge Engineering Review, 1997
As computer scientists, our goals are motivated by the desire to improve computer systems in some way: making them easier to design and implement, more robust and less prone to error, easier to use, faster, cheaper, and so on. In the field of multi-agent systems, our goal is to build systems capable of flexible autonomous decision making, with ...
Mark d'Inverno, Michael Fisher 0001, Alessio Lomuscio, Michael Luck, Maarten de Rijke, Mark Ryan 0001, Michael J. Wooldridge   +6 more
openaire   +3 more sources