Results 81 to 90 of about 20,520,278 (241)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Event-B Patterns for Specifying Fault-Tolerance in Multi-Agent Interaction

, 2007
Interaction in a multi-agent system is susceptible to failure. A rigorous development of a multi-agent system must include the specification of fault-tolerance in agent interactions for the agents to be able to continue to function independently ...
Ball, Elisabeth, Elisabeth Ball, Butler, Michael, Michael Butler   +3 more
core   +2 more sources

Multi-Agent Systems: A Survey

IEEE Access, 2018
Multi-agent systems (MASs) have received tremendous attention from scholars in different disciplines, including computer science and civil engineering, as a means to solve complex problems by subdividing them into smaller tasks. The individual tasks are allocated to autonomous entities, known as agents.
Ali Dorri, Salil S. Kanhere, Raja Jurdak
openaire   +4 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Formal Specification of Multi-Agent Systems

, 1995
In this paper the framework DESIRE, originally designed for formal specification of complex reasoning systems is used to specify a real-world multi-agent application on a conceptual level.
Keplicz, BD, Jennings, N. R., Brazier, FMT, Treur, J, Keplicz, B. D., Jennings, NR, Treur, J., Brazier, F. M. T.   +7 more
core  

Service fusion in mobile contexts [PDF]

, 2010
Service provision for mobile users poses several challenges for those managing enterprise information systems. Some of these are ubiquitous, for example, privacy and security. Others give rise to integration and interoperability issues.
Michael J. O’Grady, Jun Miao Shen, O'Hare, G. M. P. (Greg M. P.), Gregory M. P. O’Hare, Shen, J. M., O'Grady, Michael J., O\u27Grady, Michael J., O\u27Hare, G. M. P. (Greg M. P.)   +7 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Developing Industrial Multi-Agent Systems (Invited Paper)

, 1995
The development and deployment of multi-agent systems in real world settings raises a number of important research issues and problems which must be overcome if Distributed AI (DAI) is to become a widespread solution technology.
Jennings, N. R., Corera, J., Corera, J, Jennings, NR, Laresgoiti, I, Laresgoiti, I.   +5 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source