Results 61 to 70 of about 85,877 (261)

Factors affecting outcome of longer regimen multidrug-resistant tuberculosis treatment in West Java Indonesia: A retrospective cohort study.

PLoS ONE, 2021
BackgroundMultidrug-resistant tuberculosis had high treatment failure and mortality. Success rate of treatment currently 56% at global level, 48% in Indonesia and 36% in West Java province, the most populated province and surround Jakarta, the capitol of
Arto Yuwono Soeroto, Chica Pratiwi, Prayudi Santoso, Bony Wiem Lestari   +3 more
doaj   +1 more source

Computational Study on Potentially Active Antibacterial Compounds in Secondary Metabolites of Extremophilic Microorganisms

ChemistryOpen, EarlyView.
This study employed density functional theory (DFT) and conceptual DFT (CDFT) to calculate the structures and properties of potential antibacterial compounds derived from 16‐membered lactone ring‐containing secondary metabolites of extremophiles, as well as midecamycin.
Dilong Li, Yanni Wang, Yinhuan Huang, Hui Zhou, Xiaoyun Xia, Wei Huang, Chaojie Wang   +6 more
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

AGE, GENDER, EDUCATIONAL LEVEL, OCCUPATIONAL, AND KNOWLEDGE LEVEL ABOUT MULTIDRUG RESISTANT TUBERCULOSIS (MDR-TB) AMONG TUBERCULOSIS PATIENTS

Nurse and Holistic Care, 2023
Background: Resistance of Mycobacterium Tuberculosis is a condition in which Anti-Tuberculosis (OAT) drugs are unable to kill the Mycobacterium Tuberculosis germs. One type of resistance is Multidrug Resistant Tuberculosis.
Fahrur Rozi, Fakhrun Nisa’ Fiddaroini, Prawito Prawito   +2 more
doaj   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Factors associated with isoniazid resistant tuberculosis among human immunodeficiency virus positive patients in Swaziland: a case-control study

BMC Infectious Diseases, 2019
Background Isoniazid resistant tuberculosis is the most prevalent type of resistance in Swaziland and over two-thirds of the isoniazid resistant tuberculosis patients are tuberculosis and human immunodeficiency virus co-infected.
Nonhlanhla Christinah Dlamini, Dar-Der Ji, Li-Yin Chien   +2 more
doaj   +1 more source

Tuberculosis in prisons in sub-Saharan Africa--a potential time bomb. [PDF]

, 2011
No ...
Bates, Matthew, Kapata, Nathan, Mwaba, Peter, O'Grady, Justin, Zumla, Alimuddin   +4 more
core   +1 more source

Contributions of Community Advisory Board and Experience of Study Participants in TB/MDR‐TB Clinical Trial Management in Addis Ababa, Ethiopia: A Qualitative Study

Developing World Bioethics, EarlyView.
ABSTRACT Community Advisory Boards (CABs), as a form of community engagement, provide an important mechanism to ensure that research aligns with community needs and priorities by representing broader community interests and guiding research accordingly.
Yemisrach Seralegne, Abaraham G/Medihin, Ermiyas Hundito, Hawult Adane, Bizunesh Sintayehu   +4 more
wiley   +1 more source

Multidrug resistant tuberculosis.

Indian pediatrics, 1999
Multidrug-resistant tuberculosis (MDR-TB) is defined as one that is resistant to both isoniazid and rifampicin regardless of its resistance to any other antituberculosis drugs. According to "Study on the incidence of drug resistance for new admissions" reported by TB Sanatorium Council in 1992 in Japan, no increase of incidence was observed in either ...
H, Saito, R, Amitani
  +6 more sources

Multidrug-resistant and heteroresistant Mycobacterium tuberculosis and associated gene mutations in Ethiopia

International Journal of Infectious Diseases, 2015
Background: The prevalence of multidrug-resistant tuberculosis (TB) among new and retreatment cases in 2011 in Ethiopia was 2.7% and 17.9%, respectively.
Daniel Mekonnen, Aschalew Admassu, Wondemagegn Mulu, Aranzazu Amor, Agustín Benito, Woynshet Gelaye, Fantahun Biadglegne, Bayeh Abera   +7 more
doaj   +1 more source