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On the Structure and Function of Multidrug Efflux Pumps
2019Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly throughout the world and threaten to become untreatable. The origins of resistance are numerous and complex, but one underlying factor is the capacity of bacteria to rapidly export drugs through the intrinsic activity of efflux pumps.
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Multidrug Efflux Pumps and Their Inhibitors Characterized by Computational Modeling
2016Antimicrobial resistance is a key public health concern of our era due to an ever-increasing number of drug-resistant pathogens, including several Gram-negative bacilli. The latter are endowed with a low permeable outer membrane and with numerous chromosomally encoded multidrug efflux pumps, which are not only ubiquitous but also polyspecific, thus ...
RAMASWAMY, VENKATA KRISHNAN +4 more
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Chloramphenicol and expression of multidrug efflux pump in
Biochemical and Biophysical Research Communications, 2005Jean-marie Pages +2 more
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Efflux pump inhibitors of clinically relevant multidrug resistant bacteria
Medicinal Research Reviews, 2019Tihomir Tomasić +2 more
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Proceedings of the National Academy of Sciences of the United States of America, 2016
Klaas M Pos, Hanno Sjuts, Terry L Bowlin
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Klaas M Pos, Hanno Sjuts, Terry L Bowlin
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Imipenem and expression of multidrug efflux pump in
Biochemical and Biophysical Research Communications, 2003Anne Davin-Regli +2 more
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