Results 121 to 130 of about 56,538 (251)

Neuroinflammation as a result of non‐neurotropic herpesvirus infection

Immunology &Cell Biology, EarlyView.
Atypical memory B cells (ABCs) might stimulate autoreactive T cells to cause neuroinflammation and CNS myeloid cell activation during MS. Abstract The non‐neurotropic Epstein Barr virus (EBV) has been suggested to initiate the prodromal phase of multiple sclerosis (MS), often years before the first clinical symptoms. This review discusses mechanisms by
Christian Münz
wiley   +1 more source

French guidelines on systemic treatments for moderate‐to‐severe psoriasis in adults: Update 2025

Journal of the European Academy of Dermatology and Venereology, EarlyView.
New 2025 French guidelines update psoriasis management with revised algorithms integrating recent systemic therapies. They recommend methotrexate, adalimumab or ustekinumab as first‐line treatments and provide guidance for special psoriasis forms, comorbidities, pregnancy and long‐term management.
Marie Masson Regnault, Emilie Brenaut, Marie‐Emeline Marniquet, Carla Berthault, Lea Canoen, Clarisse Marcombes, Audrey Melin, Raphaël Ouakrat, Julie Charles, Stephane Mouret, Olivier Potie, Laetitia Penso, Laura Pina Vegas, Guillaume Larid, Marine Roux, Colombe Bougeard, Sandy Sylvain, Clara Labonne, Tania Randriamiarana, Da Hee Pitaud, Floriane Etheve, Jeremy Gottlieb, Laurie Gouillon, Marine Chastagner, Emilie Sbidian, Hélène Aubert, on behalf of the Psoriasis Research Group of the French Society of Dermatology (Groupe de Recherche sur le Psoriasis de la Société Française de Dermatologie), Hélène Aubert, Marie Masson Regnault, Emilie Brenaut, Emilie Sbidian, Laura Pina Vegas, Laetitia Penso, Jeremy Gottlieb, Marine Roux, Clara Labonne, Tania Randriamiarana, Floriane Etheve, Da Hee Pitaud, Marie‐Emeline Marniquet, Carla Berthault, Clarisse Marcombes, Audrey Melin, Colombe Bougeard, Julie Charles, Olivier Potie, Léa Canoen, Laurie Gouillon, Marine Chastagner, Sandy Sylvain, Guillaume Larid, Raphaël Ouakrat   +51 more
wiley   +1 more source

Neural correlates of pure apathy in multiple sclerosis: An exploratory neuroimaging study

Journal of Neuropsychology, EarlyView.
Abstract Pure apathy is relatively common in people with Multiple Sclerosis (PwMS), but its neural mechanisms remain unexplored. Therefore, we investigated the neural correlates of pure apathy in PwMS, differentiating it from depression. Sixty‐two PwMS underwent neuropsychological assessments and Magnetic Resonance Imaging scans.
Valentina Torchia, Vera Gramigna, Mariachiara Gaita, Daniele Spitaleri, Antonio Costanzo, Liana Palermo, Florindo d'Onofrio, Simona Raimo   +7 more
wiley   +1 more source

Sleep Macrostructure, Cyclic Alternating Pattern and CSF Cytokines in De Novo Relapsing–Remitting Multiple Sclerosis: A Controlled Polysomnographic Study

Journal of Sleep Research, EarlyView.
ABSTRACT Multiple sclerosis is frequently associated with sleep disorders. This study aimed to evaluate subjective and objective sleep parameters in de novo relapsing–remitting multiple sclerosis patients compared to healthy controls and to explore correlations with cerebrospinal fluid cytokines.
A. Romigi, M. Stampanoni Bassi, M. Caccamo, L. Gilio, F. Ceriello, A. Finardi, G. Vitrani, I. Rosenzweig, R. Furlan, F. Buttari, D. Centonze   +10 more
wiley   +1 more source

Psychobiotics and the microbiota–gut–brain axis: Emerging paradigms in mental health modulation

Experimental Physiology, EarlyView.
Abstract The global rise in mental health conditions has prompted interest in interventions that act beyond conventional psychopharmacology. Psychobiotics, broadly understood as live microorganisms or microbe‐derived products that interact with the microbiota–gut–brain axis, have been suggested to exert neuroactive effects through neural, immune ...
Amir Arsalan Ghahari, Mehrdad Nourizadeh, Mehrdad SalekShahabi, Shaghayegh Davari, Saeid Mohammadzadeh Mounesyar   +4 more
wiley   +1 more source

Prospective memory in patients with relapsing remitting Multiple Sclerosis [PDF]

, 2017
Prospective Memory (PM) is a set of cognitive abilities that allow us to remember to perform planned actions or delayed intentions. It requires the recall of the content of the planned task in the form of an intention to be able to execute it at the 4 ...
Cores, Evangelina Valeria, Orlando, Garcea, Osorio, Mabel, Politis, Daniel Gustavo, Vanotti, Sandra Ines   +4 more
core  

A Novel Perspective on Multiple Sclerosis: Morphological Shifts in Immune Cell Populations

Progress in Neurology and Psychiatry, Volume 30, Issue 2, May 2026.
ABSTRACT This study aims to investigate expanded hematological data in multiple sclerosis (MS) and evaluate their association with disease severity. A total of 190 patients participated in the study. For this purpose, expanded hemocytometry data were compared between 120 patients diagnosed with MS and 70 healthy controls.
Hayrettin Yavuz, Özlem Kayım Yıldız, Serkan Bolat, Demet Kablan, Selda Özer, Kübra Doğan, Şeyda Figül Gökçe, Meltem Kurt Yenihan, Halef Okan Doğan   +8 more
wiley   +1 more source

Validation of a consumer-grade activity monitor for continuous daily activity monitoring in individuals with multiple sclerosis. [PDF]

, 2019
Background:Technological advancements of remote-monitoring used in clinical-care and research require validation of model updates. Objectives:To compare the output of a newer consumer-grade accelerometer to a previous model in people with multiple ...
Block, Valerie J, Cree, Bruce Ac, Gelfand, Jeffrey M, Henry, Roland, Hollenbach, Jill A, Marcus, Gregory M, Olgin, Jeffrey E, Pletcher, Mark J, Zhao, Chao   +8 more
core  

Relapse and Neurological Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease: A Retrospective Secondary Analysis of a Japanese Nationwide Epidemiologic Survey

Clinical and Experimental Neuroimmunology, Volume 17, Issue 2, May 2026.
ABSTRACT Background Some patients with myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) experience multiple relapses and poor prognoses; however, the factors associated with these outcomes are unclear. This study aimed to identify factors associated with relapse and neurological prognosis in patients with MOGAD.
Masashi Nakamura, Juichi Fujimori, Akiyuki Uzawa, Satoshi Kuwabara, Ichiro Nakashima   +4 more
wiley   +1 more source

Why Is MS a More Frequent Complication of EBV Infection in Females?

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn, Nuria Alvarez‐Sanchez, Lawrence Steinman   +2 more
wiley   +1 more source