Results 241 to 250 of about 21,341,984 (280)

Multiple system atrophy is associated with brain somatic mutations in clonal hematopoiesis genes

open access: yes
Thompson B   +5 more
europepmc   +1 more source

Multiple System Atrophy

Continuum, 2022
Patients with multiple system atrophy (MSA) can present with diverse clinical manifestations, and the clinical care required is complex and requires a thoughtful approach to emerging symptoms and treatment decisions.Even though it is a rare disease, MSA is often encountered in clinical practice.
Werner Poewe   +8 more
openaire   +4 more sources

Multiple system atrophy

Current Opinion in Neurology, 1995
The past year has seen advances in delineating the clinical features, natural history and imaging characteristics of multiple system atrophy. The initiating pathogenetic mechanisms remain unknown. However, any aetiological or pathophysiological hypothesis must consider not only neuronal loss and gliosis but also the recently described characteristic ...
N, Quinn, G, Wenning
openaire   +4 more sources

Multiple system atrophy

The Lancet Neurology, 2004
Multiple system atrophy (MSA) is a sporadic neurodegenerative disorder characterised clinically by any combination of parkinsonian, autonomic, cerebellar, or pyramidal signs and pathologically by cell loss, gliosis, and glial cytoplasmic inclusions in several CNS structures.
Gregor K, Wenning   +3 more
openaire   +2 more sources

Young-onset multiple system atrophy

Journal of the Neurological Sciences, 2012
Han-Joon Kim   +2 more
exaly   +4 more sources

Multiple System Atrophy

Seminars in Neurology, 2014
Multiple system atrophy (MSA) is a rare adult-onset synucleinopathy associated with dysautonomia and the variable presence of poorly levodopa-responsive parkinsonism and/or cerebellar ataxia. Other clinical symptoms that can be associated with MSA include hyperreflexia, stridor, sleep apnea, and rapid eye movement sleep behavior disorder (RBD).
openaire   +2 more sources

Multiple System Atrophy

The Neurologist, 2008
It has been almost 4 decades since the descriptions of the 3 parts of multiple system atrophy (MSA) have taken place, characterized clinically by dysautonomia, parkinsonism, and cerebellar dysfunction. The discovery of a distinctive pathologic maker has finally provided the conceptual synthesis of these 3 entities into the universal designation of MSA ...
Roongroj, Bhidayasiri, Helen, Ling
openaire   +2 more sources

Multiple System Atrophy

Continuum
This article provides up-to-date diagnosis and management concepts for patients with multiple system atrophy, a rare, sporadic, adult-onset, progressive, and fatal neurodegenerative disorder that is characterized mainly by autonomic and motor dysfunction.Making an accurate and early diagnosis of multiple system atrophy remains challenging because of ...
Khemchand R. Surana   +6 more
openaire   +3 more sources

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