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Structural basis for translational regulation by RNA-binding protein Musashi-1
Structural basis for translational regulation by RNA-binding protein Musashi-1openaire
Immunohistochemical analysis of Musashi-1 expression during retinal regeneration of adult newt
Immunohistochemical analysis of Musashi-1 expression during retinal regeneration of adult newtopenaire
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Function of RNA-binding protein Musashi-1 in stem cells
Experimental Cell Research, 2005Musashi is an evolutionarily conserved family of RNA-binding proteins that is preferentially expressed in the nervous system. The first member of the Musashi family was identified in Drosophila. This protein plays an essential role in regulating the asymmetric cell division of ectodermal precursor cells known as sensory organ precursor cells through ...
Hideyuki Okano +2 more
exaly +3 more sources
Prognostic value of Musashi-1 in gliomas
Journal of Neuro-Oncology, 2013The aim of this study was to investigate the prognostic value of the RNA-binding protein Musashi-1 in adult patients with primary gliomas. Musashi-1 has been suggested to be a cancer stem cell-related marker in gliomas, and high levels of Musashi-1 have been associated with high tumor grades and hence poor prognosis.
Steinbjørn Hansen +2 more
exaly +4 more sources
Musashi-1 expression in postnatal mouse olfactory epithelium
NeuroReport, 2007We investigated the age-related change in the distribution of a molecular marker for neural stem and precursor cells, Musashi-1, in the olfactory epithelium of mice from 1 day up to 16 months of age using immunohistochemistry. We also compared the distribution pattern of Musashi-1 with that of growth-associated protein 43, the olfactory marker protein,
Kenta, Watanabe +4 more
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Identification of a putative intestinal stem cell and early lineage marker; musashi-1
Differentiation, 2003There are few reliable markers for adult stem cells and none for those of the intestinal epithelium. Previously, indirect experimental approaches have predicted stem cell position and numbers. The Musashi-1 (Msi-1) gene encodes an RNA binding protein associated with asymmetric divisions in neural progenitor cells. Two-day-old, adult, and 4.5 h, 1-, 2-,
Robert B Clarke +2 more
exaly +3 more sources
Immunohistochemical Parameters of Musashi-1 in Nodular and Diffuse Adenomyosis
Bulletin of Experimental Biology and Medicine, 2017Comparative immunohistochemical analysis of the expression of somatic stem cells marker Musashi-1 in the endometrium was performed during various phases of menstrual cycle and in patients with nodular and diffuse adenomyosis. The expression of Musashi-1 reflecting proliferative potential of epithelial and stromal cells was quantitatively analyzed by ...
I F, Kozachenko +3 more
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Assessment of MUSASHI 1 and MUSASHI 2 expression in spermatozoa and testicular tissue
Andrologia, 2021MUSASHI (MSI) family plays the main role in the spermatogenesis process. The purpose of this study was the assessment of sperm MSI1 and MSI2, and sperm functional tests in infertile men (n = 30) with varicocele and fertile men (n = 30). Furthermore, MSI1 and MSI2 proteins were assessed in testicular tissue of azoospermic men (n = 9) as well as ...
Zohreh Talebi‐Yazdabadi +7 more
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Expression patterns of chick Musashi-1 in the developing nervous system
Gene Expression Patterns, 2007Vertebrate homologues of musashi have recently been referred to as neural stem cell markers because of their expression patterns and RNA-binding interactions. In the context of the notch signaling pathway, Musashi-1 (Msi-1) is a regulator of neural cell generation, cooperating with notch to maintain mitosis.
Jonathan M, Wilson +3 more
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Knockdown of RNA Binding Protein Musashi-1 Leads to Tumor Regression In Vivo
Gastroenterology, 2008In the gut, tumorigenesis is thought to arise from the stem cell population located near the base of intestinal and colonic crypts. The RNA binding protein musashi-1 (Msi-1) is a putative intestinal and progenitor/stem cell marker. Msi-1 expression is increased during rat brain development and in APC(min/+) mice tumors.
Howard L Mcleod +2 more
exaly +3 more sources