Results 201 to 210 of about 133,873 (236)
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Muscarinic Receptor Trafficking
2011Knowledge of the mechanisms responsible for the trafficking of neurotransmitter receptors away from the cell surface is of obvious importance in understanding what regulates their expression and function. This chapter will focus on the mechanisms responsible for the internalization and degradation of muscarinic receptors.
Cindy, Reiner, Neil M, Nathanson
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Structures of muscarine picrate and muscarine tetraphenylborate
Acta Crystallographica Section C Crystal Structure Communications, 1993The tetrahydrofuran ring of the muscarine ion [(±)-(2S,4R,5S)-tetrahydro-4-hydroxy-N, N,N,5-tetramethyl-2-furanaminium] of muscarine picrate, as well as that of muscarine tetraphenylborate, is observed in a distorted twist conformation, 4 T 3 . This is different from the conformation observed in the crystal structure of muscarine chloride, but nearly ...
K. Frydenvang, B. Jensen
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Cross-tolerance between muscarinic agonists: Role of muscarinic receptors
Pharmacology Biochemistry and Behavior, 1987In order to explore the relationship between response to muscarinic agonists and brain muscarinic receptors, two mouse strains that differ in acute sensitivity (DBA and C3H) were injected chronically with DFP or infused with oxotremorine. Chronic DFP-treated DBA mice were not tolerant to DFP's effects on any measure, but they were cross-tolerant to the
A C, Collins +3 more
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Muscarinic Receptor Antagonists
2016Parasympathetic activity is increased in patients with chronic obstructive pulmonary disease (COPD) and asthma and appears to be the major reversible component of airway obstruction. Therefore, treatment with muscarinic receptor antagonists is an effective bronchodilator therapy in COPD and also in asthmatic patients.
Maria Gabriella, Matera, Mario, Cazzola
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Helvetica Chimica Acta, 1958
AbstractDie Reduktion des 2‐Methyl‐5‐dimethylaminomethyl‐2,3‐dihydro‐furan‐3‐ons wurde unter verschiedenen Bedingungen untersucht. Aus den Reduktionsprodukten wurden die Norbasen von d,l‐Muscarin, d,l‐epi‐Muscarin und d,l‐Muscaron isoliert.
C. H. Eugster +3 more
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AbstractDie Reduktion des 2‐Methyl‐5‐dimethylaminomethyl‐2,3‐dihydro‐furan‐3‐ons wurde unter verschiedenen Bedingungen untersucht. Aus den Reduktionsprodukten wurden die Norbasen von d,l‐Muscarin, d,l‐epi‐Muscarin und d,l‐Muscaron isoliert.
C. H. Eugster +3 more
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Life Sciences, 1999
Systemic administration of cholinesterase inhibitors which cross the blood brain barrier have long been known to produce analgesia and enhance analgesia from opiates. A major site of analgesic action of cholinergic agents is the spinal cord. Muscarinic receptors are concentrated in the superficial layers of the dorsal horn of the spinal cord, an area ...
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Systemic administration of cholinesterase inhibitors which cross the blood brain barrier have long been known to produce analgesia and enhance analgesia from opiates. A major site of analgesic action of cholinergic agents is the spinal cord. Muscarinic receptors are concentrated in the superficial layers of the dorsal horn of the spinal cord, an area ...
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Muscarinic Receptor Antagonists
Pulmonary Pharmacology & Therapeutics, 1999N, Watson, R M, Eglen
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PSEUDO-MUSCARINE (“SYNTHETIC MUSCARINE.”)
Journal of the American Chemical Society, 1920openaire +1 more source

