.: The functional activation of Gi/o proteins coupled to muscarinic acetylcholine receptors (mAChRs) was investigated with the conventional guanosine-5′-O-(3-[35S]thio)triphosphate ([35S]GTPγS) binding assay in rat brain membranes.
Yuji Odagaki +2 more
doaj +1 more source
Identification and Role of Muscarinic Receptor Subtypes Expressed in Rat Adrenal Medullary Cells
.: The muscarinic receptor is known to be involved in the acetylcholine (ACh)-induced secretion of catecholamines in the adrenal medullary (AM) cells of various mammals.
Keita Harada +4 more
doaj +1 more source
The regulation of M1 muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neurons1 [PDF]
Jonathon M. Willets +3 more
openalex +1 more source
Muscarinic toxin 7 (MT7) is a mamba venom peptide that binds selectively to the M1 muscarinic acetylcholine receptor. We have previously shown that the second (ECL2) and third (ECL3) extracellular loops of the M1 receptor are critically involved in ...
Katja Näreoja +2 more
doaj +1 more source
Teaching an Old Drug New Tricks: Agonism, Antagonism, and Biased Signaling of Pilocarpine through M3 Muscarinic Acetylcholine Receptor [PDF]
Alexey Pronin +2 more
openalex +1 more source
Non-Neuronal Functions of the M2 Muscarinic Acetylcholine Receptor [PDF]
Wymke Ockenga +4 more
openalex +1 more source
Non-neuronal Cholinergic Muscarinic Acetylcholine Receptors in the Regulation of Immune Function
Masato Mashimo +2 more
openalex +2 more sources
Structural homology of myelin basic protein and muscarinic acetylcholine receptor: Significance in the pathogenesis of complex regional pain syndrome [PDF]
Veronica I. Shubayev +2 more
openalex +1 more source
Molecular properties of muscarinic acetylcholine receptors
Muscarinic acetylcholine receptors, which comprise five subtypes (M1-M5 receptors), are expressed in both the CNS and PNS (particularly the target organs of parasympathetic neurons). M1-M5 receptors are integral membrane proteins with seven transmembrane segments, bind with acetylcholine (ACh) in the extracellular phase, and thereafter interact with ...
openaire +3 more sources

