Results 41 to 50 of about 1,732,495 (216)

Muscarinic M2 acetylcholine receptor distribution in the guinea-pig gastrointestinal tract [PDF]

, 2006
In the enteric nervous system, acetylcholine is the most common neurotransmitter to induce gastrointestinal smooth muscle contractions. Cholinergic signaling is mediated by muscarinic acetylcholine receptors on the surface of smooth muscle cells.
NOJYO, Yoshiaki, IINO, Satoshi
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Molecular Biological Mechanisms of Yuan Zhi Powder in the Treatment of Alzheimer’s Disease: an Analysis Based on Network Pharmacology

Digital Chinese Medicine, 2018
: Objective To predict the main active ingredients, potential targets and molecular mechanisms of Yuan Zhi powder in treatment of dementia by using network pharmacology.Methods A database of chemical constituents of Yuan Zhi powder was constructed by ...
Wei-Jie Qiang, Ying Chen, Fu-Yuan He, Mei-Feng Xiao, Wei-Yan Cai, Yi-Fei Dai, Qing Yang, Yu-Jie Li, Xiao-Gang Weng, Qi Li, Ya-Jie Wang, Xiao-Xin Zhu   +11 more
doaj   +1 more source

Tracking Voltage-Sensitive Movements of the M2 Muscarinic Acetylcholine Receptor [PDF]

Biophysical Journal, 2015
Numerous G protein-coupled receptors (GPCRs) have been shown to change their activity levels in response to changes in membrane potential. More recently, it has been directly demonstrated that these changes in activity reflect underlying changes in conformational state.
Priest, Michael F., Dekel, Noa, Barchad-Avitzur, Ofra, Ben-Chaim, Yair, Bezanilla, Francisco   +4 more
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Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone [PDF]

, 2002
Spontaneous calcium transients occur in the ventricular zone of the chick retina and result from the endogenous release of neurotransmitters in the absence of action potentials.
Catsicas, M., Peter Mobbs, Pearson, R., Pearson, Rachel; id_orcid, Becker, D., Pearson, R, Rachel Pearson, Becker, D, Mobbs, P, Becker, David, Marina Catsicas, Catsicas, Marina, Catsicas, M, Mobbs, Peter, David Becker, Mobbs, P.   +15 more
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Emerging Roles of Cholinergic Receptors in Schwann Cell Development and Plasticity

Biomedicines, 2022
The cross talk between neurons and glial cells during development, adulthood, and disease, has been extensively documented. Among the molecules mediating these interactions, neurotransmitters play a relevant role both in myelinating and non-myelinating ...
Roberta Piovesana, Adam J. Reid, Ada Maria Tata   +2 more
doaj   +1 more source

Identification and Role of Muscarinic Receptor Subtypes Expressed in Rat Adrenal Medullary Cells

Journal of Pharmacological Sciences, 2011
.: The muscarinic receptor is known to be involved in the acetylcholine (ACh)-induced secretion of catecholamines in the adrenal medullary (AM) cells of various mammals.
Keita Harada, Hidetada Matsuoka, Takeyoshi Sata, Akira Warashina, Masumi Inoue   +4 more
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Notch Signal Mediates the Cross-Interaction between M2 Muscarinic Acetylcholine Receptor and Neuregulin/ErbB Pathway: Effects on Schwann Cell Proliferation

Biomolecules, 2022
The cross-talk between axon and glial cells during development and in adulthood is mediated by several molecules. Among them are neurotransmitters and their receptors, which are involved in the control of myelinating and non-myelinating glial cell ...
Roberta Piovesana, Annalinda Pisano, Simona Loreti, Ruggero Ricordy, Claudio Talora, Ada Maria Tata   +5 more
doaj   +1 more source

Distribution of Like-muscarinic Acetylcholine Receptor M2 in the Brain of Three Castes of Polyrhachis vicina [PDF]

, 2009
The cholinergic system plays an important role in the central nervous system of insects and is closely related to the complex behavior of insects. The immunohistochemical technique was performed to detect the expression of like-muscarinic acetylcholine ...
OUYANG, Xia-hui, BU, Cui-ping, LIANG, Ai-ping, XI, Geng-si   +3 more
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Scanning curves and kinetics of the acetylcholine/acetylcholine receptor hysteresis [PDF]

, 1988
Neumann E, Boldt E, Rauer B, Wolf H, Chang HW. Scanning curves and kinetics of the acetylcholine/acetylcholine receptor hysteresis. Bioelectrochemistry and Bioenergetics.
Hendrik Wolf, Boldt, Elvira, Chang, Hai Won, Eberhard Neumann, Rauer, Barbara, Elvira Boldt, Wolf, Hendrik, Hai Won Chang, Barbara Rauer, Neumann, Eberhard   +9 more
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M2-AChR Mediates Rapid Antidepressant Effects of Scopolamine Through Activating the mTORC1-BDNF Signaling Pathway in the Medial Prefrontal Cortex

Frontiers in Psychiatry, 2021
Background: Scopolamine, a non-selective muscarinic acetylcholine receptor (M1~5-AChR) antagonist, has rapid and robust antidepressant effects in humans and other species. However, which of the five M-AChRs mediates these therapeutic effects has not been
Shuang Liu, Dandan Shi, Zuoli Sun, Yi He, Jian Yang, Jian Yang, Gang Wang, Gang Wang   +7 more
doaj   +1 more source