Results 111 to 120 of about 496,043 (271)
PLoS Pathogens, 2015 Innate immunity is regulated by cholinergic signalling through nicotinic acetylcholine receptors. We show here that signalling through the M3 muscarinic acetylcholine receptor (M3R) plays an important role in adaptive immunity to both Nippostrongylus ...
Matthew Darby +11 more
doaj +1 more source
D₂ Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways [PDF]
, 2005 Regulator of G-protein signaling 9-2 (RGS9-2), a member of the RGS family of Gα GTPase accelerating proteins, is expressed specifically in the striatum, which participates in antipsychotic-induced tardive dyskinesia and in levodopa-induced dyskinesia. We
Axelrod, Jeffrey D. +10 more
core
FASEB BioAdvances, Volume 8, Issue 3, March 2026.This study analyzed the paracellular permeability of the intestines of healthy mice at a basal level. A new detection method involving tissue incubation for 5 min with luminal fluorescent dyes, such as FM1‐43FX (FM), which bind to accessible plasma (or external) cell membranes, was developed.
Mathilde Miquel +10 more
wiley +1 more source
Medical treatment of female overactive bladder syndrome and treatment-related effects
Journal of the Formosan Medical Association, 2018 The age-adjusted prevalence of overactive bladder syndrome (OAB) in Taiwan is approximately 16.9%. Currently, a variety of treatments are available for female OAB.
Sheng-Mou Hsiao, Ho-Hsiung Lin
doaj +1 more source
Acepromazine Reduces Airway Contraction in a Murine Model of Asthma
Clinical and Experimental Pharmacology and Physiology, Volume 53, Issue 3, March 2026.ABSTRACT Acepromazine (ACP) is one of the most used sedatives in veterinary medicine, and its cardiovascular effects are well documented. In contrast, its effects on the respiratory system remain less well understood, particularly in the context of assessment of respiratory mechanics in murine models of asthma, where its use has become more common in ...
Alembert Lino‐Alvarado +6 more
wiley +1 more source
Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control
The Journal of Physiology, EarlyView.
Richard J. A. Wilson +1 more
wiley +1 more source
Allergy, Volume 81, Issue 3, Page 734-749, March 2026.This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco +38 more
wiley +1 more source
Coumarins and Their Derivatives in Animal Models of Asthma: A Systematic Review
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.Mast cells drive early allergic asthma by releasing histamine, interleukins and prostaglandins, causing airway hyperresponsiveness, mucus overproduction and inflammation. These events sustain symptoms and promote structural remodelling, contributing to the progression of the disease.
Iêda Maria dos Santos +3 more
wiley +1 more source
Bile acids differentially regulate longitudinal smooth muscle contractility in everted mouse ileum
FASEB BioAdvancesBile acids regulate gastrointestinal motility by mechanisms that are poorly understood. Standard isolated tissue bath assays might not recapitulate in vivo physiology if contractile responses to certain bile acids require direct application to the ...
Peace N. Dike +3 more
doaj +1 more source
Agonist--Antagonist--Muscarinic Receptor Ternary Complex. [PDF]
Acta Chemica Scandinavica, 1980 Britta Hedlund +4 more
openaire +2 more sources