Results 131 to 140 of about 46,071 (240)

Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 1, Page 120-130, January 2026.
This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori   +15 more
wiley   +1 more source

Positioning new pharmacotherapies for COPD

open access: yesInternational Journal of COPD, 2015
Igor Z Barjaktarevic,1 Anthony F Arredondo,1 Christopher B Cooper1,2 1Department of Medicine, 2Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA Abstract: COPD imposes ...
Barjaktarevic IZ   +2 more
doaj  

Risk of Hospitalized COVID‐19 in COPD: Single‐Inhaler Triple Versus Dual Bronchodilator Therapy

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 1, January 2026.
ABSTRACT Purpose Our objective was to estimate the effect of initiating an inhaled corticosteroids‐containing single‐inhaler triple agent (ICS‐LABA‐LAMA) compared with a single‐inhaler LABA‐LAMA dual bronchodilator in patients with COPD on the risk of severe COVID‐19 prior to the roll‐out of vaccines.
Simon Galmiche   +2 more
wiley   +1 more source

Pharmacotherapeutic Controversies During Temperature Control After Out‐of‐Hospital Cardiac Arrest: A Semi‐Structured Literature Review

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 1, January 2026.
ABSTRACT Post‐resuscitation cardiac arrest care begins at the time of hospital admission and focuses on preventing the sequelae of ischemia–reperfusion injury, including secondary brain damage and post‐cardiac arrest syndrome. Clinical practice guidelines on post‐resuscitation cardiac arrest care from international medical organizations outline ...
Christy Cecil Forehand   +17 more
wiley   +1 more source

Nicotinic and muscarinic agonists stimulate rapid protein kinase C translocation in PC12 cells [PDF]

open access: bronze, 1989
Robert O. Messing   +3 more
openalex   +1 more source

Subcutaneous Treprostinil in PH Associated With Left Heart Disease or Chronic Lung Disease

open access: yesPulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Pulmonary hypertension (PH) associated with left heart disease (LHD‐PH) and pulmonary hypertension associated with chronic lung disease (CLD‐PH) are the most common PH subtypes but lack effective treatments. In a prospective cohort study, 90 patients (39 LHD‐PH, 51 CLD‐PH) with severe disease [pulmonary vascular resistance (PVR) > 5 Wood units
Roela Sadushi‐Koliçi   +8 more
wiley   +1 more source

Marked Reversibility of Functional Small Airway Disease Following Reduction of Hazardous Inhalational Exposure: A PRM CT Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
Serial parametric response mapping (PRM)‐computed tomography revealed dynamic changes in PRM‐functional small airway disease with occupational exposure, highlighting PRM's utility for detecting and monitoring small airway disease. ABSTRACT We report a case illustrating the role of parametric response mapping (PRM) in detecting and monitoring small ...
Yeun Ho Lee   +4 more
wiley   +1 more source

Deepening insights into cholinergic agents for intraocular pressure reduction: systems genetics, molecular modeling, and in vivo perspectives

open access: yesFrontiers in Molecular Biosciences
Parasympathetic activation in the anterior eye segment regulates various physiological functions. This process, mediated by muscarinic acetylcholine receptors, also impacts intraocular pressure (IOP) through the trabecular meshwork. While FDA-approved M3
Minjae J. Kim   +4 more
doaj   +1 more source

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