Results 221 to 230 of about 52,496 (299)

The discovery of new spirocyclic muscarinic M3 antagonists

, 2010
Michael J. Stocks, Lilian Alcaraz, Andrew Bailey, Keith Bowers, David K. Donald, Helen Edwards, Fraser Hunt, Nicholas D. Kindon, Garry Pairaudeau, Jill Theaker, Daniel J. Warner   +10 more
openalex   +1 more source

An Algorithm for the Diagnosis and Management of Severe Asthma in Children and Adolescents

Allergy, Volume 81, Issue 1, Page 307-310, January 2026.
Eckard Hamelmann, Bianca Schaub, Susanne Lau, Leonard B. Bacharier   +3 more
wiley   +1 more source

Synthesis and Evaluation of Fluorinated Peptidomimetics Enabling the Development of 18F‐Labeled Radioligands Targeting Muscarinic Acetylcholine Receptor Subtype M3

ChemMedChem, Volume 20, Issue 24, December 15, 2025.
Fluorinated peptidomimetics targeting muscarinic acetylcholine receptor subtype M3: Fluorinated peptidomimetic compounds based on a β‐alanine‐glycine scaffold, with lead compound 24 demonstrating high M3 selectivity and submicromolar potency. The first M3‐selective positron emission tomography radioligand, [18F]24, is synthesized and will be evaluated ...
Miguel A. Herrera‐Rueda, Maxwell A. Boateng, Melinda Wuest, Frederick G. West, Frank Wuest   +4 more
wiley   +1 more source

Once-daily tiotropium and olodaterol fixed-dose combination via the Respimat® improves outcomes versus mono-components in COPD in two 1-year studies [PDF]

, 2014
Buhl, R, Derom, Eric, Ferguson, G, Groenke, L, Hamilton, A, Huisman, H, Korducki, L, Maltais, F, Pizzichini, E, Reid, J, Tetzlaff, K, Waitere-Wijker, S, Watz, H   +12 more
core   +1 more source

Muscarinic antagonist effects on experimental chick myopia

Experimental Eye Research, 1991
R A, Stone, T, Lin, A M, Laties
openaire   +2 more sources

Lead Generation Using Pharmacophore Mapping and Three-Dimensional Database Searching:  Application to Muscarinic M₃ Receptor Antagonists

, 1999
David P. Marriott, Iain G. Dougall, Premji Meghani, Yujiang Liu, Darren R. Flower   +4 more
openalex   +1 more source

Pharmacokinetics, metabolite profiling, safety, and tolerability of inhalation aerosol of 101BHG-D01, a novel, long-acting and selective muscarinic receptor antagonist, in healthy Chinese subjects

, 2022
Huaye Gao, Jintong Li, Xiaoping Chen, Zhan-Guo Sun, Gang Cui, Minlu Cheng, Ding Li   +6 more
openalex   +1 more source

‘BJUI Clinical Dilemma’: the overactive bladder

BJU International, Volume 137, Issue 1, Page 18-25, January 2026.
Oliver Gross, Marcio A. Averbeck, Stefania Musco, Véronique Phé, Desiree Vrijens, Blayne Welk, Glenn T. Werneburg, Thomas M. Kessler   +7 more
wiley   +1 more source

Tiotropium, a Novel Muscarinic M3 Receptor Antagonist, Improved Symptoms of Chronic Obstructive Pulmonary Disease Complicated by Chronic Heart Failure

, 2006
Mahoto Kato, Kazuo Komamura, Masafumi Kitakaze   +2 more
openalex   +2 more sources

Improving the Oral Efficacy of CNS Drug Candidates:  Discovery of Highly Orally Efficacious Piperidinyl Piperidine M₂ Muscarinic Receptor Antagonists

, 2002
Yuguang Wang, Samuel Chackalamannil, Zhiyong Hu, William J. Greenlee, John W. Clader, Craig D. Boyle, James J. Kaminski, William Billard, Binch, Gordon Crosby, Vilma Ruperto, Ruth A. Duffy, Mary Cohen-Williams, Vicki L. Coffin, Kathleen Cox, Diane E. Grotz, Jean E. Lachowicz   +16 more
openalex   +1 more source