Results 221 to 230 of about 51,230 (302)

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist [PDF]

, 2012
Kazuko Haga, Andrew C. Kruse, Hidetsugu Asada, Takami Yurugi-Kobayashi, Mitsunori Shiroishi, Cheng Zhang, William I. Weis, Tetsuji Okada, Brian K. Kobilka, Tatsuya Haga, Takuya Kobayashi   +10 more
openalex   +1 more source

The path to the G protein‐coupled receptor structural landscape: Major milestones and future directions

British Journal of Pharmacology, Volume 182, Issue 14, Page 3225-3248, July 2025.
G protein‐coupled receptors (GPCRs) play a crucial role in cell function by transducing signals from the extracellular environment to the inside of the cell. They mediate the effects of various stimuli, including hormones, neurotransmitters, ions, photons, food tastants and odorants, and are renowned drug targets.
Małgorzata M. Kogut‐Günthel, Zeenat Zara, Alessandro Nicoli, Alexandra Steuer, Marta Lopez‐Balastegui, Jana Selent, Sanjai Karanth, Melanie Koehler, Antonella Ciancetta, Layara Akemi Abiko, Franz Hagn, Antonella Di Pizio   +11 more
wiley   +1 more source

Long-acting muscarinic antagonist and long-acting β₂-agonist combination for the treatment of maintenance therapy-naïve patients with chronic obstructive pulmonary disease: a narrative review. [PDF]

Ther Adv Respir Dis
Buhl R, Miravitlles M, Anzueto A, Brunton S.   +3 more
europepmc   +1 more source

Managing Severe Asthma: A Role for the Long-Acting Muscarinic Antagonist Tiotropium. [PDF]

Biomed Res Int, 2018
Hamelmann E.
europepmc   +1 more source

Apparent capacity of cardiac muscarinic receptors for different radiolabeled antagonists☆

, 2001
Chi Shing Sum, Norman Pyo, James W. Wells   +2 more
openalex   +1 more source

Differential Modulation of Dopamine D2 Receptor on Somatostatin and Parvalbumin Interneurons in the CA1 Area of the Dorsal Hippocampus

European Journal of Neuroscience, Volume 62, Issue 1, July 2025.
In this current study, we investigated the cellular mechanisms underlying dopaminergic modulation in the hippocampus by combining pharmacology and electrophysiology in organotypic hippocampal slices. We identified that dopamine D2 receptors are expressed in somatostatin and, to a lesser extent, parvalbumin interneurons.
Pola Tuduri, Audrey Mignon, Emmanuel Valjent, Jeanne Ster   +3 more
wiley   +1 more source

Ethylatropine Bromide as a Peripherally Restricted Muscarinic Antagonist. [PDF]

ACS Chem Neurosci, 2017
Rojas A, Ganesh T, Walker A, Dingledine R.   +3 more
europepmc   +1 more source

Inhaled beta-2-agonists/muscarinic antagonists and acute myocardial infarction in COPD patients [PDF]

, 2014
Marietta Rottenkolber, Dominik Rottenkolber, Rainald Fischer, Luisa Ibáñez, Joan Fortuny, Elena Ballarín, Mónica Sabaté, Pili Ferrer, Petra Thürmann, Joerg Hasford, Sven Schmiedl   +10 more
openalex   +1 more source

5-HT2A receptor enhancement of contractile activity of the porcine urothelium and lamina propria [PDF]

, 2016
Alexander, Andersson, Baxter, Berger, Birder, Blakeman, Blanco, Bschleipfer, Chapple, Gillespie, Ikeda, Imamura, Kanai, Lecci, Liang, Masunaga, Matsumoto-Miyai, Moro, Moro, Moro, Moro, Pfeiffer, Rahnama'i, Rahnama'i, Recio, Rekik, Sadananda, Sellers, Sleight, Wang   +29 more
core   +1 more source

Feed‐induced hypersalivation in horses from Austria, Germany and Switzerland

Equine Veterinary Journal, Volume 57, Issue 4, Page 1035-1043, July 2025.
Abstract Background While previous reports come mostly from the southern Americas, several outbreaks of hypersalivation in horses were observed in Middle Europe from 2016 to 2018. Objective To describe feed‐induced hypersalivation in European horses. Study design Analysis of feedstuffs.
Linda Franziska Böswald, Christoph Gottschalk, Florian Kaltner, Joana Merk, Karin Schwaiger, Ellen Kienzle   +5 more
wiley   +1 more source