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Burden of Exacerbations in Patients Newly Initiating an Inhaled Regimen for COPD: A Claims Analysis. [PDF]
Int J Chron Obstruct Pulmon DisSethi S +7 more
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The impact of muscarinic and mGlu receptors modulators on MK-801-induced impairments in NO-dependent processes both in vitro and in vivo. [PDF]
Pharmacol RepBurnat G +3 more
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Editorial Expression of Concern for Poon et al., Targeting the muscarinic M1 receptor with a selective, brain-penetrant antagonist to promote remyelination in multiple sclerosis. [PDF]
Proc Natl Acad Sci U S Aeuropepmc +1 more source
Muscarinic receptor agonists and antagonists [PDF]
Expert Opinion on Therapeutic Patents, 1999 Although four different subtypes of the muscarinic acetylcholine (ACh) receptor with functional correlates are known to exist (function for M5 is still unclear), all muscarinic agonists and antagon...
Darius P. Zlotos +2 more
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Role of muscarinic antagonists in asthma therapy
Expert Review of Respiratory Medicine, 2017Higher parasympathetic tone has been reported in asthmatics. In general, cholinergic contractile tone is increased by airway inflammation associated with asthma. Nevertheless, the role of muscarinic antagonists for the treatment of asthma has not yet been clearly defined.
CAZZOLA, MARIO +3 more
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Selective muscarinic receptor antagonists
Trends in Pharmacological Sciences, 1984to ex- plain the anomalous binding of cholin- ergic agonists to brain receptors~ were later demonstrated with the seEective muscarinic antagonist, pirenzepine 2. Interestingly, the search for selective antagonists, which usually follows the acceptance of a concept, antedated by many years the notion of heterogeneity of rmecarinic receptors. Intuitively
R. Hammer, A. Giachetti
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