Results 101 to 110 of about 572,756 (326)
Guidelines for the Treatment of Urinary Incontineence and Overactive Bladder
South African Family Practice, 2002 Urinary incontinence (UI) is the involuntary leakage of urine, while overactive bladder (OAB) is characterised by frequency, nocturia and urgency, with or without incontinence.
C.F. Heyns, G.W. Rienhardt
doaj +1 more source
Muscarinic cholinergic receptor (M2) plays a crucial role in the development of myopia in mice
Disease Models & Mechanisms, 2013 SUMMARY Myopia is a huge public health problem worldwide, reaching the highest incidence in Asia. Identification of susceptible genes is crucial for understanding the biological basis of myopia.
Veluchamy A. Barathi +7 more
doaj +1 more source
The varieties of the psychedelic experience: A preliminary study of the association between the reported subjective effects and the binding affinity profiles of substituted phenethylamines and tryptamines [PDF]
, 2018 Classic psychedelics are substances of paramount cultural and neuroscientific importance. A distinctive feature of psychedelic drugs is the wide range of potential subjective effects they can elicit, known to be deeply influenced by the internal state of
Erowid, Earth +6 more
core +2 more sources
An Algorithm for the Diagnosis and Management of Severe Asthma in Children and Adolescents
Allergy, EarlyView.ABSTRACT Severe asthma (SA) in childhood is infrequent (≈2% of all paediatric asthma), yet it drives a disproportionate share of morbidity and cost. A clear algorithm is required to distinguish difficult‐to‐treat asthma (DTA) from true SA and to guide phenotype‐driven diagnosis and therapy.
Eckard Hamelmann +3 more
wiley +1 more source
Muscarinic Receptor Antagonists: Effects on Pulmonary Function [PDF]
, 2011 In healthy lungs, muscarinic receptors control smooth muscle tone, mucus secretion, vasodilation, and inflammation. In chronic obstructive pulmonary disease (COPD) and asthma, cholinergic mechanisms contribute to increased bronchoconstriction and mucus secretion that limit airflow.
Allison D. Fryer, Kalmia S. Buels
openaire +3 more sources
Andrology, EarlyView.Abstract Couple infertility is a very ancient medical condition. One of the first descriptions of familial infertility/subfertility is contained in the first book of the Bible, Genesis, written in the 10th century BC and reporting tales from the oral tradition even occurred about 800 years earlier.
Manuela Simoni +2 more
wiley +1 more source
The therapeutic potential of allosteric ligands for free fatty acid sensitive GPCRs [PDF]
, 2013 G protein coupled receptors (GPCRs) are the most historically successful therapeutic targets. Despite this success there are many important aspects of GPCR pharmacology and function that have yet to be exploited to their full therapeutic potential.
Hudson, Brian D. +2 more
core +1 more source
Journal of Neuroscience, 2004 Using a dialysis probe near CA1 hippocampal recording electrodes, we infused nonspecific (scopolamine) and specific (methoctramine, pirenzepine) antagonists of muscarinic cholinergic transmission to determine their effects on the positional firing ...
E. Brazhnik +3 more
semanticscholar +1 more source
Acta Ophthalmologica, EarlyView.Abstract To determine the effectiveness of various interventions in reducing myopia progression in children. Literature databases were searched on December 2, 2023: PubMed, Embase, the Cochrane Central, Web of Science Core Collection, BIOSIS Previews, Current Contents Connect, Data Citation Index, Derwent Innovations Index, KCI‐Korean Journal Database,
Diana Chabané Schmidt +9 more
wiley +1 more source
PHARMACOLOGICAL APPROACH IN EXERCISE-INDUCED ASTHMA [PDF]
Sport Mont, 2012 Exercise-induced asthma is a transient airflow obstruction, which occurs after the strenuous exercise. It is a complex pathophysiological phenomenon, present in all levels of exercise, from children to professional athletes, so the therapy is specific ...
Biljana Vitošević +2 more
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