Results 121 to 130 of about 18,712 (165)

Acute Effects of Four Major Trace Amines on Zebrafish Behavioral, Neurochemical, and Neuroendocrine Responses

open access: yesJournal of Neurochemistry, Volume 169, Issue 6, June 2025.
A trace amine beta‐phenylethylamine is anxiolytic and reduces brain acetylcholine at 12 μg/L, but elevates anxiety and cortisol levels at 1000 μg/L. Acute tryptamine at 7 mg/L is anxiogenic, reduces shoaling and social interaction, but elevates brain acetylcholine and cortisol levels. Acute tyramine at 15 μg/L, and octopamine at 125, 500, and 1500 μg/L,
Thalia M. Quintanilha   +10 more
wiley   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Direct Stimulation of Gastric Smooth Muscle Cells via Gq Proteins With Light

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 6, June 2025.
Optogenetic stimulation enables direct and selective stimulation of smooth muscle cells and thus provides a new opportunity to restore gastric contractility in cases of gastroparesis. Herein, we demonstrate that hOPN5 is a new and effective tool acting via Gq signaling and is thus complementary to light‐induced membrane depolarization with ...
David Zipf   +6 more
wiley   +1 more source

Autonomic Nervous System in Bone Remodeling: From Mechanisms to Novel Therapies in Orthopedic Diseases

open access: yesOrthopaedic Surgery, Volume 17, Issue 6, Page 1561-1576, June 2025.
Due to the close connection between the autonomic nervous system and skeletal system, large amounts of evidence have shown that neuromodulation plays a crucial role in regulating bone metabolism. Clinically, neuromodulation has exhibited promising therapeutic effects in treating joint disorders by significantly reducing inflammation and clinical scores.
Ruihao Xia   +7 more
wiley   +1 more source

Treatable Trait Guided Asthma Management: A Feasibility Study

open access: yesRespirology, Volume 30, Issue 6, Page 480-492, June 2025.
ABSTRACT Background and Objectives Treatable trait‐based personalised medicine improves outcomes in severe asthma clinics. We assessed the feasibility of a randomised controlled trial (RCT) of protocolised treatable trait‐guided asthma management in patients not under a severe asthma clinic. Methods Ten week single‐group cohort study.
James Fingleton   +37 more
wiley   +1 more source

Sex and age differences in the association between heart rate variability and cardiac chronotropy: A replication‐extension study

open access: yesPhysiological Reports, Volume 13, Issue 11, June 2025.
Abstract Using heart rate variability (vmHRV) as a proxy of cardiac vagal modulation, previous studies have hinted at sex differences in the vagal control of cardiac chronotropy in young adults, but little is known in older individuals. The current study aimed at investigating for the first time the moderating role of both sex and age in the ...
Luca Carnevali   +7 more
wiley   +1 more source

Key lines of discovery in myopia research

open access: yes
Ophthalmic and Physiological Optics, Volume 45, Issue 4, Page 899-902, June 2025.
Frank Schaeffel   +3 more
wiley   +1 more source

Muscarinic antagonist effects on experimental chick myopia

open access: yesExperimental Eye Research, 1991
Ton Lin   +2 more
openaire   +2 more sources

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