Results 121 to 130 of about 578,217 (295)

Analysis of ligand binding to receptors by competition kinetics. Application to muscarinic antagonists in rat brain cortex.

, 1985
Gabriel Schreiber, Yoav I. Henis, Mordechai Sokolovsky   +2 more
openalex   +1 more source

Spontaneous enteric nervous system activity generates contractile patterns prior to maturation of gastrointestinal motility

Neurogastroenterology &Motility, EarlyView.
Spontaneous neuronal network activity is critical for circuit maturation, yet whether this is a feature of enteric nervous system development has yet to be established. Here, we identify clustered ripples, a previously undescribed form of neurogenic gastrointestinal motility that shares many features with spontaneous neuronal networks in other systems.
Lori B. Dershowitz, Hassler Bueno Garcia, Andrew S. Perley, Todd P. Coleman, Julia A. Kaltschmidt   +4 more
wiley   +1 more source

D₂ Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways [PDF]

, 2005
Regulator of G-protein signaling 9-2 (RGS9-2), a member of the RGS family of Gα GTPase accelerating proteins, is expressed specifically in the striatum, which participates in antipsychotic-induced tardive dyskinesia and in levodopa-induced dyskinesia. We
Axelrod, Jeffrey D., Barghshoon, Sami, Chen, Ching-Kang, Cheyette, Benjamin N. R., Ebert, Jana, Kovoor, Abraham, Lester, Henry A., Schwarz, Johannes, Schwarz, Sigrid, Seyffarth, Petra, Simon, Melvin I.   +10 more
core  

Krisanaklan Reduces Intestinal Anion and Fluid Secretion Through Inhibition of Na+/K+‐ATPase and K+ Channel Activity

Annals of the New York Academy of Sciences, EarlyView.
Krisanaklan reduces CFTR‐dependent intestinal chloride and fluid secretion by inhibiting the Na+,K+‐ATPase and K+ channels in epithelial cells. Consequently, this natural, plant‐derived product may limit secretory diarrhea caused by a diverse array of microbial pathogens. However, by dissipating the transmembrane Na+ gradient, Krisanaklan also inhibits
Tessa A. Groeneweg, Erdene Baigal, Anny Leung, Gert‐Jan Kremers, Marcel J. C. Bijvelds   +4 more
wiley   +1 more source

Binding and functional profiles of the selective M₁muscarinic receptor antagonists trihexyphenidyl and dicyclomine [PDF]

, 1986
Antonio Giachetti, E. Giraldo, H. Ladinsky, E. Montagna   +3 more
openalex   +1 more source

The Association Between Use of Inhaled Corticosteroids and Long‐Acting Beta2‐Agonists During Pregnancy and Adverse Fetal Outcomes

Respirology, EarlyView.
This study updated safety evidence on ICS and LABA use in pregnant women with asthma. After adjusting confounders, there was no association between ICS or LABA use and adverse fetal outcomes. However, high‐dose ICS exposure was associated with a higher risk of congenital anomalies among ICS users.
Yea‐Chwen Wu, I‐Te Wang, Hsin‐Yi Huang, Chung‐Hsuen Wu   +3 more
wiley   +1 more source

Diphenylsulfone muscarinic antagonists: piperidine derivatives with high m2 selectivity and improved potency

, 2000
William Billard, Herbert Binch, Kristen Bratzler, Lian-Yong Chen, Gordon Crosby, Ruth A. Duffy, Sundeep Dugar, Jean E. Lachowicz, Robert McQuade, Pradeep Pushpavanam, Vilma Ruperto, Lisa A. Taylor, John W. Clader   +12 more
openalex   +1 more source

Effects of the Selective M1 Muscarinic Receptor Antagonist Dicyclomine on Emotional Memory [PDF]

, 2000
Raquel Vecchio Fornari, Karin Di Monteiro Moreira, Maria Gabriela Menezes Oliveira   +2 more
openalex   +1 more source

Intraocular Pressure Increase Induced by 0.5% Tropicamide‐0.5% Phenylephrine in Dogs: An Analysis of Causes Using Ultrasound Biomicroscopy

Veterinary Ophthalmology, EarlyView.
ABSTRACT Purpose To determine whether the differences in intraocular pressure (IOP) change after the topical application of 0.5% tropicamide and 0.5% phenylephrine (TP) are due to anatomical variations in the anterior chamber using ultrasound biomicroscopy (UBM).
Donghee Kim, Sang‐Eun Park, Haerin Yoon, Jiyi Hwang, Ji Seung Jung, Soohyun Kim, Kyung‐Mee Park   +6 more
wiley   +1 more source

Efficacy and safety of muscarinic antagonists as add-on therapy for male lower urinary tract symptoms [PDF]

, 2014
Jinhong Li, Qingquan Shi, Yunjin Bai, Chunxiao Pu, Yin Tang, Haichao Yuan, Yunjian Wu, Qiang Wei, Ping Han   +8 more
openalex   +1 more source