Results 171 to 180 of about 687,004 (308)

Profile of a fixed-dose combination of tiotropium/olodaterol and its potential in the treatment of COPD

International Journal of COPD, 2015
Sanjeevan Muruganandan,1 Lata Jayaram2,3 1Department of Respiratory and Sleep Medicine, Austin Health, 2Department of Respiratory and Sleep Medicine, Western Health, 3University of Melbourne, Melbourne, Victoria, Australia Abstract: Chronic obstructive
Muruganandan S, Jayaram L
doaj  

Emerging role of long acting muscarinic antagonists for asthma

British Journal of Clinical Pharmacology, 2014
B. Lipworth
semanticscholar   +1 more source

Game Changers in the Treatment of and Engagement With Persons Living With Mental Health and Substance Use Disorders: The Role of the Nurse

International Journal of Mental Health Nursing, Volume 35, Issue 2, April 2026.
ABSTRACT The game changers in mental health and substance use disorder treatment have been shaped by historical sea changes marked by transformative advancements that have significantly enhanced patient care. Breakthroughs in psychotherapy, psychosurgery and psychopharmacology have each contributed to reshaping clinical practices, especially the ...
Arlene Kent‐Wilkinson, Sudor Ogunwemimo, Eileen Zaba   +2 more
wiley   +1 more source

The role of agomelatine in appetite regulation and body weight in rats

Experimental Physiology, Volume 111, Issue 4, Page 1808-1818, 1 April 2026.
Abstract The hypothalamic nuclei play a central role in the synthesis of anorexigenic and orexigenic neuropeptides, which are regulated by peripheral hormones, like leptin and ghrelin. Melatonergic receptors (MT1/MT2) are prominently expressed in the arcuate nucleus of the hypothalamus – an essential hub for appetite control – and in peripheral ...
Engin Korkmaz, Yavuz Erden, Çiğdem Tekin, Suat Tekin   +3 more
wiley   +1 more source

Isometric handgrip contraction increases tibialis anterior intrinsic motoneuron excitability in a dose‐dependent manner

Experimental Physiology, Volume 111, Issue 4, Page 2200-2213, 1 April 2026.
Abstract The contribution of persistent inward currents (PICs) to motoneuron firing in the lower limb typically increases after a remote handgrip contraction, believed to result from diffuse serotonergic input increases in spinal cord. We investigated whether handgrip contraction intensity, duration and/or impulse would affect PIC estimates in tibialis
Lucas Ugliara, Lucas B. R. Orssatto, Amilton Vieira, Gabriel S. Trajano   +3 more
wiley   +1 more source

5-HT2A receptor enhancement of contractile activity of the porcine urothelium and lamina propria [PDF]

, 2016
Alexander, Andersson, Baxter, Berger, Birder, Blakeman, Blanco, Bschleipfer, Chapple, Gillespie, Ikeda, Imamura, Kanai, Lecci, Liang, Masunaga, Matsumoto-Miyai, Moro, Moro, Moro, Moro, Pfeiffer, Rahnama'i, Rahnama'i, Recio, Rekik, Sadananda, Sellers, Sleight, Wang   +29 more
core   +1 more source

Evening administration of long-acting muscarinic antagonists in COPD - a randomized controlled trial. [PDF]

BMC Pulm Med
Sivapalan P, Rømer V, Jordan A, Johansen ND, Pareek M, Modin D, Mathioudakis AG, Vestbo J, Vognsen AK, Eklöf J, Hurst JR, Klausen TW, Biering-Sørensen T, Jensen JS.   +13 more
europepmc   +1 more source

Long-acting muscarinic receptor antagonists for the treatment of chronic airway diseases

Therapeutic Advances in Chronic Disease, 2014
K. Alagha, A. Palot, T. Sofalvi, L. Pahus, M. Gouitaa, C. Tummino, S. Martinez, D. Charpin, A. Bourdin, P. Chanez   +9 more
semanticscholar   +1 more source

Long-Acting Muscarinic Antagonists for the Treatment of Difficult-to-Treat and Severe Asthma: A Narrative Review Focusing on Inflammation from Bench to Bedside. [PDF]

J Inflamm Res
Calzetta L, Manzetti GM, Pistocchini E, Lauro RF, Gholamalishahi S, Cazzola M, Rogliani P.   +6 more
europepmc   +1 more source

Use of long-acting muscarinic antagonists for severe asthma: insights from clinicians in the SHARP network. [PDF]

Respir Res
Marcon A, Martinelli L, Bansal AT, Berret E, Bossios A, Marchetti P, Porsbjerg C, Principe S, Schleich F, Sergejeva S, Sont JK, Caminati M.   +11 more
europepmc   +1 more source