Results 81 to 90 of about 22,691 (214)

Prescription Patterns of New Use of Fixed-Dose Combination Inhalers in Patients with Chronic Obstructive Pulmonary Disease: Long-Acting β2 Agonists Plus Long-Acting Muscarinic Antagonists versus Long-Acting β2 Agonists Plus Inhaled Corticosteroids. [PDF]

Int J Chron Obstruct Pulmon Dis, 2023
Liao PA, Pan SW, Chen CY, Deng CY, Dong YH.   +4 more
europepmc   +1 more source

Effects of temperature and ethanol on agonist and antagonist binding to rat heart muscarinic receptors in the absence and presence of GTP [PDF]

, 1985
Magalì Waelbroeck, Patrick Robberecht, Pierre Chatelain, Philippe De Neef, Jean Christophe   +4 more
openalex   +1 more source

Risk Assessment of Acute Myocardial Infarction and Stroke Associated with Long-Acting Muscarinic Antagonists, Alone or in Combination, versus Long-Acting beta2-Agonists. [PDF]

Int J Chron Obstruct Pulmon Dis, 2022
Rebordosa C, Plana E, Rubino A, Aguado J, Martinez D, Lei A, Daoud S, Saigi-Morgui N, Perez-Gutthann S, Rivero-Ferrer E.   +9 more
europepmc   +1 more source

Clinical predictors of treatment response to tiotropium add-on therapy in adult asthmatic patients: From multicenter real-world cohort data in Korea

World Allergy Organization Journal, 2022
Background: Tiotropium, a long-acting muscarinic antagonist, is recommended for add-on therapy to inhaled corticosteroids (ICS)-long-acting beta 2 agonists (LABA) for severe asthma.
Ji-Su Shim, MD, PhD, Juhae Jin, MA, Sae-Hoon Kim, MD, PhD, Taehoon Lee, MD, PhD, An-Soo Jang, MD, PhD, Chan Sun Park, MD, PhD, Jae-Woo Jung, MD, PhD, Jae-Woo Kwon, MD, PhD, Ji-Yong Moon, MD, PhD, Min-Suk Yang, MD, PhD, Jaechun Lee, MD, PhD, Jeong-Hee Choi, MD, PhD, Yoo Seob Shin, MD, PhD, Hee-Kyoo Kim, MD, PhD, Sujeong Kim, MD, PhD, Joo-Hee Kim, MD, PhD, Sang-Heon Cho, MD, PhD, Young-Hee Nam, MD, PhD, Sang-Hoon Kim, MD, PhD, So Young Park, MD, PhD, Gyu Young Hur, MD, PhD, Sang-Ha Kim, MD, PhD, Hye-Kyung Park, MD, PhD, Hyun Jung Jin, MD, PhD, Jae-Hyun Lee, MD, PhD, Jung-Won Park, MD, PhD, Ho Joo Yoon, MD, PhD, Byoung Whui Choi, MD, PhD, Young-Joo Cho, MD, PhD, Min-Hye Kim, MD, PhD, Tae-Bum Kim, MD, PhD   +30 more
doaj  

Muscarinic Receptor Agonists and Antagonists: Effects on Cancer [PDF]

, 2011
Many epithelial and endothelial cells express a cholinergic autocrine loop in which acetylcholine acts as a growth factor to stimulate cell growth. Cancers derived from these tissues similarly express a cholinergic autocrine loop and ACh secreted by the cancer or neighboring cells interacts with M3 muscarinic receptors expressed on the cancer cells to ...
openaire   +3 more sources

The Forefront for Novel Therapeutic Agents Based on the Pathophysiology of Lower Urinary Tract Dysfunction: Ameliorative Effect of Solifenacin Succinate (Vesicare ®), a Bladder-Selective Antimuscarinic Agent, on Overactive Bladder Symptoms, Especially Urgency Episodes

Journal of Pharmacological Sciences, 2010
Overactive bladder (OAB) syndrome is a common condition that is most often observed in the elderly. Pharmacological treatment with muscarinic receptor antagonists has been most widely used for OAB. An antimuscarinic agent, solifenacin, showed the highest
Akiyoshi Ohtake, Shuichi Sato, Masao Sasamata, Keiji Miyata   +3 more
doaj  

Effects of treatment with long-acting muscarinic antagonists (LAMA) and long-acting beta-agonists (LABA) on lung function improvement in patients with bronchiectasis: an observational study. [PDF]

J Thorac Dis, 2021
Lee SY, Lee JS, Lee SW, Oh YM.
europepmc   +1 more source

Umeclidinium bromide/vilanterol combination in the treatment of chronic obstructive pulmonary disease: a review

Therapeutics and Clinical Risk Management, 2015
Dionisios Spyratos, Lazaros Sichletidis Pulmonary Department, “G Papanikolaou” Hospital, Aristotle University of Thessaloniki, Exohi, Thessaloniki, Greece Abstract: Chronic obstructive pulmonary disease (COPD) is a common disease ...
Spyratos D, Sichletidis L
doaj  

The Modulation Of Detrusor Contractility By Agents Influencing Ion Channel Activity

European Pharmaceutical Journal, 2018
Background: This study specified the role of several significant ion channels regulating the metabolism of calcium ions in contraction and relaxation of human detrusor muscle in order to identify possible target for future drugs that are capable of ...
Kocmálová M., Ľupták J., Barboríková J., Kazimierová I., Grendár M., Šutovský J.   +5 more
doaj   +1 more source

Lung deposition of inhaled once-daily long-acting muscarinic antagonists via standard jet nebulizer or dry powder inhaler, measured using functional respiratory imaging, in patients with chronic obstructive pulmonary disease. [PDF]

Ther Adv Respir Dis, 2022
Crater GD, Johnson K, Ward J, Backer J.
europepmc   +1 more source