Results 141 to 150 of about 2,360,825 (374)

Obesity drives the link between liver fat and depression: Cross‐sectional and prospective investigations

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Inconsistent associations have been reported between steatotic liver disease (SLD) and depression. We aimed to investigate the cross‐sectional and prospective associations between MRI‐derived liver fat, SLD and depression. Materials and Methods We used UK Biobank data. Liver fat was measured with liver MRI proton density fat fraction. SLD
Qi Feng   +3 more
wiley   +1 more source

Hyperhidrosis: don't sweat it

open access: yesInternal Medicine Journal, EarlyView.
Abstract Hyperhidrosis is an under‐reported and under‐treated condition that causes significant patient morbidity. Secondary causes require consideration, but the vast majority of cases are idiopathic. The condition is encountered by a range of clinicians, including neurologists, dermatologists and endocrinologists, and it pays to be familiar with the ...
Mitchell J. Lycett, Karl Ng
wiley   +1 more source

Muscarinic Receptors in Developmental Axonal Competition at the Neuromuscular Junction. [PDF]

open access: yesMol Neurobiol, 2023
Tomàs J   +9 more
europepmc   +1 more source

Effect of SGLT‐2 inhibitors on COPD exacerbations in individuals with type 2 diabetes: A meta‐analysis and Bayesian sensitivity analysis

open access: yesJournal of Diabetes Investigation, EarlyView.
This systematic review and meta‐analysis evaluates the impact of SGLT‐2 inhibitors on COPD exacerbations in patients with Type 2 diabetes mellitus (T2DM). Our findings demonstrate that SGLT‐2 inhibitors significantly reduce the frequency of COPD exacerbations by 35% compared to other antidiabetic agents, offering dual benefits in glycemic control and ...
Muhammed Shabil   +14 more
wiley   +1 more source

Muscarinic cannabinoid suppression of excitation, a novel form of coincidence detection

open access: yesPharmacological Research
Δ9-tetrahydrocannabinol (THC), the chief psychoactive ingredient of cannabis, acts in the brain primarily via cannabinoid CB1 receptors. These receptors are implicated in several forms of synaptic plasticity – depolarization-induced suppression of ...
Michaela Dvorakova   +2 more
doaj  

Histamine H1 Receptor Down-Regulation Mediated by M3 Muscarinic Acetylcholine Receptor Subtype

open access: yesJournal of Pharmacological Sciences, 2004
Heterologous down-regulation of histamine H1 receptor (H1R) mediated by muscarinic acetylcholine receptor subtype was investigated using five kinds of Chinese hamster ovary (CHO) cells stably co-expressing the human H1R and one of the five (M1 –M5 ...
Katsuhiro Miyoshi   +5 more
doaj  

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer   +4 more
wiley   +1 more source

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