Results 61 to 70 of about 8,003 (176)

Enhancing Wholemeal Bread Shelf Life Using Optimized Mixtures of Cinnamon, Clove, and Bay Leaf Essential Oils

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT This study evaluated the preservative potential of essential oils (EOs) in bakery products by identifying fungal contaminants in bread, testing the in vitro antifungal activity of a mixture of cinnamon, clove, and bay leaf EOs, and assessing their effectiveness in extending shelf life. Fungal identification revealed the presence of Penicillium,
Mariana Pereira Silveira, Karine Guimarães Moreira, Míriam Aparecida de Aguilar Santos, Irene Andressa, Mateus Alves Araújo, Nathalia de Andrade Neves, Franciele Maria Pelissari, Marcio Schmiele   +7 more
wiley   +1 more source

Role of calcium in the analgesic action of tetrahydroisoxazolepyridinol and muscimol

Journal of Pharmacy and Pharmacology, 1991
Abstract The role of calcium in the analgesic activity of 4,5,6,7-tetrahydroisoxazole-(5,4-c) pyrídin-3-ol (THIP) and muscimol has been investigated using the acetic acid assay procedure. THIP and muscimol produced significant analgesic response.
S, Rajaram, S, Ramaswamy, J S, Bapna
openaire   +2 more sources

Sevoflurane Inhibits Layer 5 Pyramidal Neurons via Kv1.2‐Dependent Modulation of Subthreshold Currents

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
General anesthetics suppress cortical activity, but their cellular mechanisms remain unclear. We investigated how the volatile anesthetic sevoflurane affects layer 5 pyramidal neurons in the auditory cortex. Using patch‐clamp recordings and computational modeling, we found that low‐dose sevoflurane reduces neuronal firing through Kv1.2 channel ...
Aelton S. Araujo, Gabriel M. de Queiroz, Sérgio Ruschi B. Silva, Werner Treptow, Katarina E. Leao   +4 more
wiley   +1 more source

Study of the effect of GABAA receptore and glial inhibition on behavioral responses in CCI model of neuropathic pain in rat

Iranian South Medical Journal, 2015
Background: The mechanisms underlying neuropathic pain are complex and remain controversial. From the proposed mechanisms we can refer to loss of GABAergic inhibition and glial activation in the spinal dorsal horn.
Mehi Sadeghi, Homa Manaheji, Abbad Haghparast, Jalal Zaringhalam, Samad Nazemi, Zahra Bahari   +5 more
doaj  

Selective Functional Interaction Between the Lateral Habenula and Hippocampus During Different Tests of Response Flexibility

Frontiers in Molecular Neuroscience, 2019
The lateral habenula (LHb) has been shown to play critical roles in a variety of appetitive tasks (e.g., spatial memory and object recognition) that require animals to flexibly respond to changing task conditions.
Phillip M. Baker, Yingxue Rao, Zeena M. G. Rivera, Esteli M. Garcia, Sheri J. Y. Mizumori, Sheri J. Y. Mizumori   +5 more
doaj   +1 more source

Evaluation of the GABAA Receptor Expression and the Effects of Muscimol on the Activity of Wide Dynamic Range Neurons Following Chronic Constriction Injury of Sciatic Nerve in Rats

Basic and Clinical Neuroscience, 2021
Introduction: The modality of γ-aminobutyric acid type a receptors (GABAA) controls dorsal horn neuronal excitability and inhibits sensory information.
Mehdi Sadeghi, Homa Manaheji, Jalal Zaringhalam, Abbas Haghparast, Samad Nazemi, Zahra Bahari, Seyed Mohammad Noorbakhsh   +6 more
doaj  

The inactivation of the basolateral nucleus of the rat amygdala has an anxiolytic effect in the elevated T-maze and light/dark transition tests

Brazilian Journal of Medical and Biological Research, 2005
Pharmacological evidence indicates that the basolateral nucleus of the amygdala (BLA) is involved in the mediation of inhibitory avoidance but not of escape behavior in the elevated T-maze test.
C.H. Bueno, H. Zangrossi Jr., M.B. Viana
doaj   +1 more source

Hippocampal GABAA Receptor and Pain Sensitivity during Estrous Cycle in the Rat [PDF]

Iranian Journal of Medical Sciences, 2011
Background: Estradiol and progesterone as well as hippocampal GABAA receptors are believed to play a role in the modulation of pain. The aim of present study was to investigate the effect of intrahippocampal injections of GABAA receptor agonist (muscimol)
Mahnaz Taherianfard, Mahnaz Mosavi
doaj  

Emerging Risks of Amanita Muscaria: Case Reports on Increasing Consumption and Health Risks

Acta Medica Lituanica
Introduction: The increasing popularity of Amanita muscaria, driven by its hallucinogenic properties, has raised significant public health concerns, particularly as it remains largely unregulated across most European Union countries.
Emilija Savickaitė, Gabija Laubner-Sakalauskienė   +1 more
doaj   +1 more source

The Role of Parabrachial GABAA Receptors in Pain Modulation in Rats [PDF]

Journal of Fasa University of Medical Sciences, 2013
Background & Objective: The parabrachial nucleus is a critical link in the transmission of short latency nociceptive information to midbrain neurons.
kazem javanmardi, ava soltanihekmat, masoomeh shekoohi, parisa hasanein, mehdi bakhshi, roghayeh ghodsi, leila rezaeian   +6 more
doaj   +1 more source