Results 41 to 50 of about 8,003 (176)

Effects of Ethanol on Sensory Inputs to the Medial Giant Interneurons of Crayfish

open access: yesFrontiers in Physiology, 2018
Crayfish are capable of two rapid, escape reflexes that are mediated by two pairs of giant interneurons, the lateral giants (LG) and the medial giants (MG), which respond to threats presented to the abdomen or head and thorax, respectively.
Matthew E. Swierzbinski, Jens Herberholz
doaj   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, Volume 13, Issue 29, 22 May 2026.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

Neurotoxicity associated with the medicinal mushroom product-Diamond Shruumz: A case report

open access: yesToxicology Reports
Medicinal mushrooms are widely available as health supplements, and the federal government does not currently require these products to be examined for quality and contents.
Elizabeth F. Ebbens   +3 more
doaj   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, Volume 40, Issue 5, Page 2604-2631, May 2026.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

Inactivation of the Medial-Prefrontal Cortex Impairs Interval Timing Precision, but Not Timing Accuracy or Scalar Timing in a Peak-Interval Procedure in Rats

open access: yesFrontiers in Integrative Neuroscience, 2018
Motor sequence learning, planning and execution of goal-directed behaviors, and decision making rely on accurate time estimation and production of durations in the seconds-to-minutes range. The pathways involved in planning and execution of goal-directed
Catalin V. Buhusi   +6 more
doaj   +1 more source

Equipped for success: genomes and metabolomes of the European Amanita muscaria are conserved in its novel South African range

open access: yesNew Phytologist, Volume 250, Issue 3, Page 1863-1883, May 2026.
Summary Plants and soils have been moved around the world for centuries, but invasive mushrooms receive scant attention. The Amanita muscaria species complex was introduced to South Africa in the context of forestry, but its origins, ecology and recent evolution are unstudied. We sequenced the genomes of 24 Northern and Southern Hemisphere A. muscaria,
Grant R. Nickles   +39 more
wiley   +1 more source

GABAergic Control of Nigrostriatal and Mesolimbic Dopamine in the Rat Brain

open access: yesFrontiers in Behavioral Neuroscience, 2018
Purpose: The present study assessed the effects of the GABAA receptor (R) agonist muscimol (MUS), and the GABAAR antagonist bicuculline (BIC) on neocortical and subcortical radioligand binding to dopamine D2/3Rs in relation to motor and exploratory ...
Susanne Nikolaus   +10 more
doaj   +1 more source

Direct Analysis of Psilocin and Muscimol in Urine Samples Using Single Drop Microextraction Technique In-Line with Capillary Electrophoresis

open access: yesMolecules, 2020
The fully automated system of single drop microextraction coupled with capillary electrophoresis (SDME-CE) was developed for in-line preconcentration and determination of muscimol (MUS) and psilocin (PSC) from urine samples.
Anna Poliwoda   +2 more
doaj   +1 more source

Reevaluating the role of the hippocampus in delay eyeblink conditioning. [PDF]

open access: yesPLoS ONE, 2013
The role of the hippocampus in delay eyeblink conditioning (DEC) remains controversial. Here, we investigated the involvement of the hippocampus in DEC with a soft tone as the conditioned stimulus (CS) by using electrolytic lesions or muscimol ...
Guang-yan Wu   +7 more
doaj   +1 more source

Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature

open access: yesEcology and Evolution, Volume 16, Issue 4, April 2026.
This study explores the evolutionary role of psilocybin, the psychedelic compound found in Psilocybe mushrooms. We provide the first experimental tests of defence and community‐level evidence for invertebrate responses to psilocybin‐producing fungi, revealing significant negative effects on invertebrate locomotion, development, and survival.
K. J. Matthews Nicholass   +16 more
wiley   +1 more source

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